Detailed information of TA system TA147625

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1630963..1631143
• Replicon: chromosome
• Accession: NZ_CP047782
• Organism: Staphylococcus aureus strain UP_1352

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: E3T04_RS08050
• Protein ID: WP_001801861.1
• Coordinates: 1630963..1631058 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1631086..1631143 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3T04_RS08020	1626107..1626733	+	627	WP_000669038.1	hypothetical protein	-
E3T04_RS08025	1626774..1627118	+	345	WP_000627550.1	DUF3969 family protein	-
E3T04_RS08030	1627216..1627788	+	573	WP_000414222.1	hypothetical protein	-
E3T04_RS08035	1627937..1629304	-	1368	WP_001093574.1	FRG domain-containing protein	-
E3T04_RS08040	1629304..1629873	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
E3T04_RS08045	1630066..1630512	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
E3T04_RS08050	1630963..1631058	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1631086..1631143	-	58	-	-	Antitoxin
E3T04_RS08055	1631181..1631282	+	102	WP_001791232.1	hypothetical protein	-
E3T04_RS08060	1631457..1631900	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
E3T04_RS08065	1631900..1632343	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
E3T04_RS08070	1632343..1632785	-	443	Protein_1584	DUF1433 domain-containing protein	-
E3T04_RS08075	1633310..1635730	+	2421	WP_000182553.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T147625 WP_001801861.1 NZ_CP047782:1630963-1631058 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T147625 NZ_CP063153:2098410-2098586 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTGGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCAAGGGCGACGCAGTGTCATGCCGCGTCACCCCAGTGATGAGATAAAAGAACCATTGCGTAAAGCAATCCTGAAGC
AACTCGGTTTGAGTTAA

Antitoxin

Nucleotide

• Length: 58 bp

>AT147625 NZ_CP047782:c1631143-1631086 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin