Detailed information of TA system TA147603

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1180891..1181071
• Replicon: chromosome
• Accession: NZ_CP047781
• Organism: Staphylococcus aureus strain UP_1452

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: E3T07_RS05910
• Protein ID: WP_001801861.1
• Coordinates: 1180891..1180986 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1181014..1181071 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3T07_RS05880	1176035..1176661	+	627	WP_000669038.1	hypothetical protein	-
E3T07_RS05885	1176702..1177046	+	345	WP_000627550.1	DUF3969 family protein	-
E3T07_RS05890	1177144..1177716	+	573	WP_000414222.1	hypothetical protein	-
E3T07_RS05895	1177865..1179232	-	1368	WP_001093574.1	FRG domain-containing protein	-
E3T07_RS05900	1179232..1179801	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
E3T07_RS05905	1179994..1180440	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
E3T07_RS05910	1180891..1180986	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1181014..1181071	-	58	-	-	Antitoxin
E3T07_RS05915	1181109..1181210	+	102	WP_001791232.1	hypothetical protein	-
E3T07_RS05920	1181385..1181828	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
E3T07_RS05925	1181828..1182271	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
E3T07_RS05930	1182271..1182713	-	443	Protein_1183	DUF1433 domain-containing protein	-
E3T07_RS05935	1183238..1185658	+	2421	WP_000182553.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T147603 WP_001801861.1 NZ_CP047781:1180891-1180986 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T147603 NZ_CP063147:c4771653-4771369 [Klebsiella pneumoniae]
ATGACCTATGAACTGGAGTTTGATCCACGAGCCTGGCGCGAATGGCAGAAGCCTGGCGAGACGGTCAAAAAACAGTTCAA
AAATAAGCTCCAGCAGATTGTGCAGAATCCGCGAATTGAGTCGGCCAGGCTGAGCGATTTACCGGATTGCTACAAAATCA
AGCTTAAGGCGTCAGGTTATCGGTTGGTGTATCAAGTACGAGATAGTGTGGTGGTGGTTTACGTTATTGCCATTGGCAAA
AGAGAGAAAGCGGCCGTTTATCATCAGGCGAATAAACGGCTCTAA

Antitoxin

Nucleotide

• Length: 58 bp

>AT147603 NZ_CP047781:c1181071-1181014 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin