Detailed information of TA system TA147580

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 1834359..1834543
• Replicon: chromosome
• Accession: NZ_CP047780
• Organism: Staphylococcus aureus strain UP_1539

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: A0A2P7CQJ7
• Locus tag: E3T11_RS08695
• Protein ID: WP_000482647.1
• Coordinates: 1834359..1834466 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	1834483..1834543 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3T11_RS08670	1829731..1830204	+	474	WP_000456492.1	GyrI-like domain-containing protein	-
E3T11_RS08675	1830327..1831538	-	1212	WP_001192075.1	multidrug effflux MFS transporter	-
E3T11_RS08680	1831720..1832379	-	660	WP_000831295.1	hypothetical protein	-
E3T11_RS08685	1832439..1833581	-	1143	WP_001176863.1	glycerate kinase	-
E3T11_RS08690	1833839..1834225	+	387	WP_000779360.1	flippase GtxA	-
E3T11_RS08695	1834359..1834466	+	108	WP_000482647.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	1834483..1834543	-	61	-	-	Antitoxin
E3T11_RS08700	1835170..1836933	+	1764	WP_001064836.1	ABC transporter ATP-binding protein/permease	-
E3T11_RS08705	1836958..1838691	+	1734	WP_000486496.1	ABC transporter ATP-binding protein/permease	-
E3T11_RS08710	1838922..1839089	+	168	WP_001792506.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (6-89)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4012.76 Da
• Isoelectric Point: 10.4935

>T147580 WP_000482647.1 NZ_CP047780:1834359-1834466 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T147580 NZ_CP047780:1834359-1834466 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin

Nucleotide

• Length: 61 bp

>AT147580 NZ_CP047780:c1834543-1834483 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Toxin

• AlphaFold DB: A0A2P7CQJ7

Antitoxin