Detailed information of TA system TA147573

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1957455..1957671
• Replicon: chromosome
• Accession: NZ_CP047779
• Organism: Staphylococcus aureus strain UP_1559

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: E3T12_RS09945
• Protein ID: WP_073392962.1
• Coordinates: 1957567..1957671 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	1957455..1957510 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3T12_RS09925	1952548..1952868	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
E3T12_RS09930	1952870..1953850	+	981	WP_000019741.1	CDF family zinc efflux transporter CzrB	-
E3T12_RS09935	1954116..1955207	+	1092	WP_000495684.1	hypothetical protein	-
E3T12_RS09940	1955495..1957141	+	1647	WP_000277741.1	IS1182-like element ISSau3 family transposase	-
-	1957455..1957510	+	56	-	-	Antitoxin
E3T12_RS09945	1957567..1957671	-	105	WP_073392962.1	hypothetical protein	Toxin
E3T12_RS09950	1958351..1958509	+	159	WP_001792784.1	hypothetical protein	-
E3T12_RS09955	1959168..1960025	-	858	WP_103246171.1	Cof-type HAD-IIB family hydrolase	-
E3T12_RS09960	1960093..1960875	-	783	WP_000908186.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	1955495..1957141	1646

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T147573 WP_073392962.1 NZ_CP047779:c1957671-1957567 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T147573 NZ_CP063073:2655145-2655396 [Pseudomonas poae]
GTGTCCAAAAATGAAAAGCTGCTCGCCAAACTGCTCAACGAGCGCATGGCCTTTACCTGGCCAGAGCTCGAAACGCTACT
CAAGCGTCTTGGCTACACACAGATTGAAGGGGCCGGAAGCCGGGTCAAATTCGACATCGGCGACCCCAGTGCAATGATCA
CCTTGCACAGGCCTCACCCCGGCAACGAACTGAAACACTACATTCGGCGCCAGATCATCGAACAATTGAAATCAGGAGAA
CTGATTCAGTGA

Antitoxin

Nucleotide

• Length: 56 bp

>AT147573 NZ_CP047779:1957455-1957510 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Antitoxin