Detailed information of TA system TA147564

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1580928..1581108
• Replicon: chromosome
• Accession: NZ_CP047779
• Organism: Staphylococcus aureus strain UP_1559

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: E3T12_RS07685
• Protein ID: WP_001801861.1
• Coordinates: 1580928..1581023 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1581051..1581108 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3T12_RS07655	1576072..1576698	+	627	WP_000669038.1	hypothetical protein	-
E3T12_RS07660	1576739..1577083	+	345	WP_000627550.1	DUF3969 family protein	-
E3T12_RS07665	1577181..1577753	+	573	WP_000414222.1	hypothetical protein	-
E3T12_RS07670	1577902..1579269	-	1368	WP_160190036.1	FRG domain-containing protein	-
E3T12_RS07675	1579269..1579838	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
E3T12_RS07680	1580031..1580477	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
E3T12_RS07685	1580928..1581023	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1581051..1581108	-	58	-	-	Antitoxin
E3T12_RS07690	1581146..1581247	+	102	WP_001791232.1	hypothetical protein	-
E3T12_RS07695	1581422..1581864	-	443	Protein_1505	DUF1433 domain-containing protein	-
E3T12_RS07700	1581864..1582307	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
E3T12_RS07705	1582307..1582749	-	443	Protein_1507	DUF1433 domain-containing protein	-
E3T12_RS07710	1583274..1585694	+	2421	WP_000182553.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T147564 WP_001801861.1 NZ_CP047779:1580928-1581023 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T147564 NZ_CP063056:c2475870-2474590 [Rodentibacter sp. DSM 111151]
ATGGATAATTCAATACTTAATGTTGCAATGAATGGTATTTTAGTTGGTTGGTGGCGACGTTTAAAAAATGGGGCTACAGA
ATTTCAATATGCCGAAAAATGGCTTTCGTCTGTCCGATCCCGCCCCATTTCGCTTTCATTGCCGCTTTCATCAAAAATTT
ATCGTGGTGATGAAGTATATAATTTTTTTGATAATTTATTACCTGATAACGAACACATTCGTTCTCGTATTCAACAGCGT
TTTCAAACCAATACGAAAACACCTTTTGATTTGCTGTCCGCAATTGGGCAAGACTGTGTCGGCGCAATACAGCTTTATCA
GCACAACACAGATTTTGTAAAAACAGTGTATGCTGAACCATTGTCTGAATTTGAAATTGAAAACACACTAAAAAACTACC
GCACTTTTCCACTTGGAATGGAGCAGGAAGAAAACTTTCGTATATCCATTGCCGGTGCACAGGAAAAAACCGCTTTACTG
AACTATAACGGGCAATGGATGCGCCCTTTATATACCACCCCAACCAGCCATATTTTTAAATTACCGATAGGAATGGTCGC
TCAAAATCAACTCGATCTTTCCAACAGTTGTGAAAATGAATGGCTTTGTTTAAGAATTATGCAAGTTCTCGGATTAAAAG
TCCCTTTTTCCGCTATTGAACATTTTGGGGAAATTAAAACGTTAATTGTCGAACGTTTTGATCGCCGATGGTCTGAAGAT
AGAAAATGGCTCATTCGATTGCCACAAGAAGATATGTGCCAAGCATTAAATACAGCCCCAGCCAGAAAATATGAAAGTGA
TGGCGGTCCCGGCATTTTACAAATTATGCAATTATTAAATGGTTCAGCAAATCCGAATGAAGATAGAAAACAATTCTTTA
AAGCACAAATTGTCTTTTGGTTACTTTGTGCTATTGATGGACATGCTAAAAATTTTAGTATTTTTTTAGAGCCCAAAGGG
CATTATCGTTTGACACCATTTTATGATGTCATATCCGCTTACCCTTTGATTAAAGCTCAGGGATTAGCCAAGCAAAAAGT
CAAAATGGCAATGGCTTGGTATGGCGAAAATAAACACTATTTGTGGGATAAAATTCAACTTCGTCATATTTTTGCTACCG
CTAAATTAGTCGGTTTGTCTAAAACTGTCGTTGAAGATATTCTTCAAGAAATTTTGACTTGTTTGCCGAAAATTGATCTC
ATTGCAATTTCTCACCTACCAAATGAAGTTAGTGAACCGATTTTAGTCGGGTTAAAAAAACAAGCTCAAAAAATTCTATA
A

Antitoxin

Nucleotide

• Length: 58 bp

>AT147564 NZ_CP047779:c1581108-1581051 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin