Detailed information of TA system TA147545

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1093166..1093363
• Replicon: chromosome
• Accession: NZ_CP047778
• Organism: Staphylococcus aureus strain UP_1572

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: E3T13_RS05485
• Protein ID: WP_000623369.1
• Coordinates: 1093256..1093363 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	1093166..1093203 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3T13_RS05450	1088359..1088646	-	288	WP_000410718.1	hypothetical protein	-
E3T13_RS05455	1088987..1089277	+	291	WP_001791476.1	hypothetical protein	-
E3T13_RS05460	1089365..1090006	-	642	WP_000571191.1	ABC transporter ATP-binding protein	-
E3T13_RS05465	1090003..1090323	-	321	WP_000873929.1	YxeA family protein	-
E3T13_RS05470	1090326..1092290	-	1965	WP_000870819.1	bacteriocin-associated integral membrane family protein	-
E3T13_RS05475	1092334..1092606	-	273	WP_001794574.1	lactococcin 972 family bacteriocin	-
E3T13_RS05480	1092616..1092717	-	102	WP_001790623.1	hypothetical protein	-
-	1093166..1093203	+	38	-	-	Antitoxin
E3T13_RS05485	1093256..1093363	-	108	WP_000623369.1	putative holin-like toxin	Toxin
E3T13_RS05490	1093634..1094236	-	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
E3T13_RS05495	1094251..1094427	-	177	WP_000214898.1	YkvS family protein	-
E3T13_RS05500	1094626..1095612	+	987	WP_000668820.1	lipoate--protein ligase	-
E3T13_RS05505	1095693..1095911	-	219	WP_000876825.1	IDEAL domain-containing protein	-
E3T13_RS05510	1096121..1096690	+	570	WP_000287265.1	competence protein ComK	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T147545 WP_000623369.1 NZ_CP047778:c1093363-1093256 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T147545 NZ_CP063046:2491760-2491867 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAGCTGGCTGAACAAGCGGAAGTAA

Antitoxin

Nucleotide

• Length: 38 bp

>AT147545 NZ_CP047778:1093166-1093203 [Staphylococcus aureus]
AACATGTCGCCTAATGAGCCCGTTAAAAAGACGGTGAC

Structures

Antitoxin