Detailed information of TA system TA147520

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 176342..176522
• Replicon: chromosome
• Accession: NZ_CP047777
• Organism: Staphylococcus aureus strain UP_1632

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: E3T16_RS01095
• Protein ID: WP_001801861.1
• Coordinates: 176427..176522 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	176342..176399 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3T16_RS01065	172051..172185	+	135	WP_001791797.1	hypothetical protein	-
E3T16_RS01070	172349..173905	+	1557	WP_000028669.1	type I restriction-modification system subunit M	-
E3T16_RS01075	173898..175127	+	1230	WP_000072627.1	restriction endonuclease subunit S	-
E3T16_RS01080	175579..176073	+	495	Protein_176	transposase	-
E3T16_RS01085	176064..176225	+	162	Protein_177	transposase	-
E3T16_RS01090	176203..176304	-	102	WP_001792025.1	hypothetical protein	-
-	176342..176399	+	58	-	-	Antitoxin
E3T16_RS01095	176427..176522	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
E3T16_RS01100	176667..177679	+	1013	Protein_180	IS3 family transposase	-
E3T16_RS01105	177877..178449	-	573	WP_000414216.1	hypothetical protein	-
E3T16_RS01110	178550..178891	-	342	WP_000627540.1	DUF3969 family protein	-
E3T16_RS01115	178932..179558	-	627	WP_160177496.1	hypothetical protein	-
E3T16_RS01120	179633..180628	-	996	WP_000070642.1	DUF4352 domain-containing protein	-
E3T16_RS01125	180709..181359	-	651	WP_001795210.1	excalibur calcium-binding domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk / hlgA / lukD	149509..200540	51031

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T147520 WP_001801861.1 NZ_CP047777:c176522-176427 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T147520 NZ_CP063019:4157336-4157554 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA

Antitoxin

Nucleotide

• Length: 58 bp

>AT147520 NZ_CP047777:176342-176399 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin