Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | sprG-sprF/- |
| Location | 2126655..2126934 | Replicon | chromosome |
| Accession | NZ_CP047646 | ||
| Organism | Staphylococcus aureus strain 19/Msa0875 | ||
Toxin (Protein)
| Gene name | SprG3 | Uniprot ID | Q2FWA7 |
| Locus tag | GQ601_RS10080 | Protein ID | WP_001802298.1 |
| Coordinates | 2126655..2126759 (+) | Length | 35 a.a. |
Antitoxin (RNA)
| Gene name | SprF3 | ||
| Locus tag | - | ||
| Coordinates | 2126755..2126934 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GQ601_RS10055 (GQ601_10105) | 2122105..2122872 | - | 768 | WP_001095317.1 | IS21-like element helper ATPase IstB | - |
| GQ601_RS10060 (GQ601_10110) | 2122884..2124119 | - | 1236 | WP_001215401.1 | IS21 family transposase | - |
| GQ601_RS10065 (GQ601_10115) | 2124302..2125159 | + | 858 | WP_000370942.1 | HAD family hydrolase | - |
| GQ601_RS10070 (GQ601_10120) | 2125289..2125381 | - | 93 | WP_000220902.1 | hypothetical protein | - |
| GQ601_RS10075 (GQ601_10125) | 2125817..2125975 | - | 159 | WP_001792784.1 | hypothetical protein | - |
| GQ601_RS10080 (GQ601_10130) | 2126655..2126759 | + | 105 | WP_001802298.1 | hypothetical protein | Toxin |
| - | 2126755..2126934 | - | 180 | - | - | Antitoxin |
| GQ601_RS10085 (GQ601_10135) | 2127257..2128348 | - | 1092 | WP_000495673.1 | hypothetical protein | - |
| GQ601_RS10090 (GQ601_10140) | 2128614..2129594 | - | 981 | WP_000019735.1 | CDF family zinc efflux transporter CzrB | - |
| GQ601_RS10095 (GQ601_10145) | 2129596..2129916 | - | 321 | WP_000003759.1 | Zn(II)-responsive metalloregulatory transcriptional repressor CzrA | - |
| GQ601_RS10100 (GQ601_10150) | 2130068..2130733 | + | 666 | WP_001024099.1 | SDR family oxidoreductase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 35 a.a. Molecular weight: 3906.77 Da Isoelectric Point: 5.5724
>T147018 WP_001802298.1 NZ_CP047646:2126655-2126759 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
Download Length: 105 bp
>T147018 NZ_CP062851:c2390976-2390800 [Escherichia coli O9:H10]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA
Antitoxin
Download Length: 180 bp
>AT147018 NZ_CP047646:c2126934-2126755 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
