Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | SprA2-SprA2AS/- |
Location | 1828733..1828917 | Replicon | chromosome |
Accession | NZ_CP047646 | ||
Organism | Staphylococcus aureus strain 19/Msa0875 |
Toxin (Protein)
Gene name | SprA2 | Uniprot ID | A0A2P7CQJ7 |
Locus tag | GQ601_RS08540 | Protein ID | WP_000482647.1 |
Coordinates | 1828733..1828840 (+) | Length | 36 a.a. |
Antitoxin (RNA)
Gene name | SprA2AS | ||
Locus tag | - | ||
Coordinates | 1828857..1828917 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
GQ601_RS08515 (GQ601_08565) | 1824090..1824563 | + | 474 | WP_000456489.1 | GyrI-like domain-containing protein | - |
GQ601_RS08520 (GQ601_08570) | 1824686..1825897 | - | 1212 | WP_001191974.1 | multidrug effflux MFS transporter | - |
GQ601_RS08525 (GQ601_08575) | 1826085..1826744 | - | 660 | WP_000831300.1 | hypothetical protein | - |
GQ601_RS08530 (GQ601_08580) | 1826804..1827946 | - | 1143 | WP_001176859.1 | glycerate kinase | - |
GQ601_RS08535 (GQ601_08585) | 1828213..1828599 | + | 387 | WP_000779355.1 | flippase GtxA | - |
GQ601_RS08540 (GQ601_08590) | 1828733..1828840 | + | 108 | WP_000482647.1 | type I toxin-antitoxin system Fst family toxin | Toxin |
- | 1828857..1828917 | - | 61 | - | - | Antitoxin |
GQ601_RS08545 (GQ601_08595) | 1829544..1831307 | + | 1764 | WP_001064818.1 | ABC transporter ATP-binding protein | - |
GQ601_RS08550 (GQ601_08600) | 1831332..1833065 | + | 1734 | WP_000486511.1 | ABC transporter ATP-binding protein | - |
GQ601_RS08555 (GQ601_08605) | 1833296..1833463 | + | 168 | WP_001798790.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 36 a.a. Molecular weight: 4012.76 Da Isoelectric Point: 10.4935
>T147015 WP_000482647.1 NZ_CP047646:1828733-1828840 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK
Download Length: 108 bp
>T147015 NZ_CP062851:c1772559-1772182 [Escherichia coli O9:H10]
ATGAAAACATTACCCGACACGCATGTACGGGAGGTATCGTGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCACTACGGCCTTACGCTGAATGACACACCGTTCGTGGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGACGCGGTGAACTTTCTCGTTGAAAAATACGCGCTGGTACGTACCGACCAGTCGGGATTC
AGCGCCTGTACCCACTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCTCGCCGGGCAACAGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGGAAGCATCCGGAGGCGAAACGATGA
ATGAAAACATTACCCGACACGCATGTACGGGAGGTATCGTGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCACTACGGCCTTACGCTGAATGACACACCGTTCGTGGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGACGCGGTGAACTTTCTCGTTGAAAAATACGCGCTGGTACGTACCGACCAGTCGGGATTC
AGCGCCTGTACCCACTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCTCGCCGGGCAACAGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGGAAGCATCCGGAGGCGAAACGATGA
Antitoxin
Download Length: 61 bp
>AT147015 NZ_CP047646:c1828917-1828857 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|