Detailed information of TA system TA145965

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1980291..1980509
• Replicon: chromosome
• Accession: NZ_CP047321
• Organism: Staphylococcus aureus strain RJ1267

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: GSF72_RS09950
• Protein ID: WP_044122766.1
• Coordinates: 1980405..1980509 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	1980291..1980346 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GSF72_RS09910	1975387..1976412	-	1026	WP_048665747.1	restriction endonuclease subunit S	-
GSF72_RS09915	1976399..1978303	-	1905	WP_048665742.1	N-6 DNA methylase	-
GSF72_RS09920	1978458..1978643	-	186	WP_001286805.1	hypothetical protein	-
GSF72_RS09925	1978645..1978755	-	111	WP_000139425.1	hypothetical protein	-
GSF72_RS09930	1978827..1978955	-	129	WP_000884149.1	hypothetical protein	-
GSF72_RS09935	1979181..1979936	-	756	WP_000861027.1	CHAP domain-containing protein	-
GSF72_RS09940	1979948..1980202	-	255	WP_159343896.1	phage holin	-
GSF72_RS09945	1980254..1980349	+	96	Protein_1914	hypothetical protein	-
-	1980283..1980376	+	94	NuclAT_0	-	-
-	1980283..1980376	+	94	NuclAT_0	-	-
-	1980283..1980376	+	94	NuclAT_0	-	-
-	1980283..1980376	+	94	NuclAT_0	-	-
-	1980291..1980346	+	56	-	-	Antitoxin
GSF72_RS09950	1980405..1980509	-	105	WP_044122766.1	hypothetical protein	Toxin
GSF72_RS09955	1980705..1981079	-	375	WP_048665740.1	hypothetical protein	-
GSF72_RS09960	1981113..1981397	-	285	WP_000400415.1	hypothetical protein	-
GSF72_RS14815	1981441..1981608	-	168	WP_000421095.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1978458..2020333	41875

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3932.77 Da
• Isoelectric Point: 5.5724

>T145965 WP_044122766.1 NZ_CP047321:c1980509-1980405 [Staphylococcus aureus]
MLLLERNSMSDFEMLMVVLTIIGLVLISNQDHKK

Nucleotide

• Length: 105 bp

>T145965 NZ_CP062713:3065247-3065525 [Escherichia coli O157:H7]
ATGTTACCCGTGTTATGGCTTGAAAGCGCAGATACCGACCTAGATGATATAACTAGTTATATTGCTCGTTTCGACATAGA
TGCGGCTGAACGCTTATGGCAGCGATTAAGGGGTTGTGTGCTGCCGTTATCCGAACATCCGTATTTATACCCACCAAGCG
ACAGAGTACCTGGCTTGCGTGAGATTGTAGCCCACCCTAACTATATAATTCTATACCGCGTAACAACATCAAGCGTTGAA
GTAGTAAACGTGATCCACGCAAGACGCCAGTTTCCCTAA

Antitoxin

Nucleotide

• Length: 56 bp

>AT145965 NZ_CP047321:1980291-1980346 [Staphylococcus aureus]
AAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Antitoxin