145941

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1804266..1804966 Replicon chromosome
Accession NZ_CP047311
Organism Pseudomonas putida strain YC-AE1

Toxin (Protein)


Gene name mqsR Uniprot ID A0A2I0CDW7
Locus tag GR140_RS08160 Protein ID WP_003254238.1
Coordinates 1804266..1804562 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID I7AUJ7
Locus tag GR140_RS08165 Protein ID WP_003254235.1
Coordinates 1804565..1804966 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GR140_RS08140 (GR140_08135) 1799902..1801527 + 1626 WP_003254243.1 twin-arginine translocation signal domain-containing protein -
GR140_RS08145 (GR140_08140) 1801649..1802125 + 477 WP_003254241.1 sigma-70 family RNA polymerase sigma factor -
GR140_RS08150 (GR140_08145) 1802294..1802773 + 480 WP_003254240.1 hypothetical protein -
GR140_RS08155 (GR140_08150) 1802846..1804171 + 1326 WP_212628363.1 MFS transporter -
GR140_RS08160 (GR140_08155) 1804266..1804562 + 297 WP_003254238.1 type II toxin-antitoxin system MqsR family toxin Toxin
GR140_RS08165 (GR140_08160) 1804565..1804966 + 402 WP_003254235.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
GR140_RS08170 (GR140_08165) 1805038..1806702 - 1665 WP_232858901.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
GR140_RS08175 (GR140_08170) 1807256..1808005 + 750 WP_003254232.1 electron transfer flavoprotein subunit beta/FixA family protein -
GR140_RS08180 (GR140_08175) 1808007..1808948 + 942 WP_047604111.1 FAD-binding protein -
GR140_RS08185 (GR140_08180) 1809024..1809845 + 822 WP_003254229.1 transporter substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(6-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-109)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11110.18 Da        Isoelectric Point: 10.2270

>T145941 WP_003254238.1 NZ_CP047311:1804266-1804562 [Pseudomonas putida]
MEKRMPNCPLERVKALAAARRIRPTGAALKGAKALGMDFPGMLEVITSLKRTDFYKSMTSHIDHRVWQDVYRPLTAIGYV
YLKLSVVDDVLIVSFKEL

Download         Length: 297 bp

>T145941 NZ_CP062711:3594448-3594735 [Escherichia coli O157:H7]
ATGTTACCCATTTTATGGCTACCGTCTGCTCGCGATGATTTGCGCCAGATCATAACTTACATCGCCAAGGAGAACCCACC
GGCAGCACGTAGACTAAAAATACGCATTGAAACATCGGTATTACCTCTATCTGAGCATCCGTACTTATATCCACCAAGCG
AACGGGTTTCTGGATTGAGAGAGATCGTGACCCACCCTAACTACATAATCCTGTACAGAGTAGCTGCTTCAAGCATTGAG
ATTGTAAGCGTGACACATTCTCGGCGACAATTTCCCTTCTCTATCTGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14684.76 Da        Isoelectric Point: 4.9531

>AT145941 WP_003254235.1 NZ_CP047311:1804565-1804966 [Pseudomonas putida]
MRCPICGGSELAPDIQGMPYSYKGEMTVIPEVSGDYCSACGECVLSHDEAMRVSHLMTAFERQVNANVVDPSFIASIRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA

Download         Length: 402 bp

>AT145941 NZ_CP062711:3594257-3594448 [Escherichia coli O157:H7]
ATGGGTACAGCCCTTTCTCCGATAGTTTCAGAATTCGAAACTACCGAACAAGAAAACAGTTACAACGAATGGTTGCGCAC
TAAAGTAACGTCAAGCCTTGCAGACACTCGCCCCGCAATTCCACATGACGAGGTAATGGCTGAAATGGAAAATCTTATTG
CTCAAATTGCTGTAACTAACAAGAGCGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I0CDW7

Antitoxin

Source ID Structure
AlphaFold DB I7AUJ7

References