Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | mqsRA (relBE)/MqsR-MqsA |
| Location | 458070..458776 | Replicon | chromosome |
| Accession | NZ_CP047171 | ||
| Organism | Xylella fastidiosa subsp. fastidiosa strain IVIA5235 | ||
Toxin (Protein)
| Gene name | mqsR | Uniprot ID | Q87EE2 |
| Locus tag | D1605_RS01875 | Protein ID | WP_004090696.1 |
| Coordinates | 458070..458372 (+) | Length | 101 a.a. |
Antitoxin (Protein)
| Gene name | mqsA | Uniprot ID | Q87EE1 |
| Locus tag | D1605_RS01880 | Protein ID | WP_004090697.1 |
| Coordinates | 458375..458776 (+) | Length | 134 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| D1605_RS01840 | 453838..454557 | - | 720 | Protein_344 | phage late control D family protein | - |
| D1605_RS01845 | 454457..455428 | - | 972 | WP_011097609.1 | hypothetical protein | - |
| D1605_RS01850 | 455436..455993 | - | 558 | WP_011097610.1 | phage tail protein I | - |
| D1605_RS01855 | 455986..456879 | - | 894 | WP_011097611.1 | baseplate J/gp47 family protein | - |
| D1605_RS01860 | 456879..457217 | - | 339 | WP_004090694.1 | GPW/gp25 family protein | - |
| D1605_RS01865 | 457415..457696 | + | 282 | WP_004090695.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| D1605_RS01870 | 457707..457982 | + | 276 | WP_004085172.1 | HigA family addiction module antidote protein | - |
| D1605_RS01875 | 458070..458372 | + | 303 | WP_004090696.1 | type II toxin-antitoxin system MqsR family toxin | Toxin |
| D1605_RS01880 | 458375..458776 | + | 402 | WP_004090697.1 | type II toxin-antitoxin system MqsA family antitoxin | Antitoxin |
| D1605_RS01885 | 458845..459432 | - | 588 | WP_011097612.1 | phage baseplate assembly protein V | - |
| D1605_RS01890 | 459429..459971 | - | 543 | WP_011097613.1 | hypothetical protein | - |
| D1605_RS01895 | 459947..460468 | - | 522 | WP_011097614.1 | hypothetical protein | - |
| D1605_RS01900 | 460465..460788 | - | 324 | WP_011097935.1 | hypothetical protein | - |
| D1605_RS01905 | 460788..461048 | - | 261 | WP_011097616.1 | hypothetical protein | - |
| D1605_RS01910 | 461066..462940 | - | 1875 | WP_011097617.1 | phage major capsid protein | - |
| D1605_RS01915 | 462937..463569 | - | 633 | WP_011097618.1 | phage portal protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 446013..468846 | 22833 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 10948.71 Da Isoelectric Point: 8.0251
>T145531 WP_004090696.1 NZ_CP047171:458070-458372 [Xylella fastidiosa subsp. fastidiosa]
MEKGTSHYKLPVVKALVKAGKVRATATAYQGARELGIKDLTGMCTVVLALTSADFYKSMTTYADHTVFQDVYHAKTASGD
EVYLKLTVIDDVLIVSFKEL
MEKGTSHYKLPVVKALVKAGKVRATATAYQGARELGIKDLTGMCTVVLALTSADFYKSMTTYADHTVFQDVYHAKTASGD
EVYLKLTVIDDVLIVSFKEL
Download Length: 303 bp
>T145531 NZ_CP062402:c1867139-1866987 [Staphylococcus aureus]
ATGTCTAAAGACAAAGATCCAAAATTAAATTATCATGAAGAAGAAAACAGTATGGTAACGGATTTTGAAGATTTAAAAGA
ATTAGGTAAAGAAATGGAACAAATTTCTGATCAAAATGATCAAGAAAAGAATTCTGAAGAAGACAGTCAGTAA
ATGTCTAAAGACAAAGATCCAAAATTAAATTATCATGAAGAAGAAAACAGTATGGTAACGGATTTTGAAGATTTAAAAGA
ATTAGGTAAAGAAATGGAACAAATTTCTGATCAAAATGATCAAGAAAAGAATTCTGAAGAAGACAGTCAGTAA
Antitoxin
Download Length: 134 a.a. Molecular weight: 14944.02 Da Isoelectric Point: 7.1650
>AT145531 WP_004090697.1 NZ_CP047171:458375-458776 [Xylella fastidiosa subsp. fastidiosa]
MRCPCCGAAELIHDTRDMLYTYKSETTSIPTVTGDFCPACGEVVLDREHGDRYSELVGLFQRQVNSAYVDPGYITKVRRK
LDLDQRQAAELFGGGVNAFSRYENGKTKPPLSLVKLFKLLDRHPDLLNEVKSS
MRCPCCGAAELIHDTRDMLYTYKSETTSIPTVTGDFCPACGEVVLDREHGDRYSELVGLFQRQVNSAYVDPGYITKVRRK
LDLDQRQAAELFGGGVNAFSRYENGKTKPPLSLVKLFKLLDRHPDLLNEVKSS
Download Length: 402 bp
>AT145531 NZ_CP062402:c1867763-1867164 [Staphylococcus aureus]
ATGGCAATGAACTTTAAAGTCTTTGACAATAGTCAACTTGTAGCAGAATATGCTGCTGATATTATTAGAAAGCAATTTAA
CAATAATCCTACTACAATTGCAGGTTTTCATTTAGATACAGATCAAGCGCCAGTTCTAGATGAATTAAAGAAAAATGTTG
AAAAACATGCTGTTGATTTTAGCCAAATAAATATTTTAGATTATGACGATAAAAAATCATATTTCGAAGGGTTAGGTGTA
CCAGCAGGTCAAGTTTATCCAATTGCTTATGAAAAAGATGCAATCGAATTAATCGCTGATAAGATTAAAACTAAAGAAAA
TAAAGGGAAATTAACATTACAAGTTGTTTCTATCGATGAGCAAGGTAAGTTAAATGTTAGTATTCGTCAAGGACTAATGG
AAGCAAGAGAAATTTTCTTAGTAGTGACAGGTGCTAATAAACGAGATGTAGTTGAAAAATTATATCAAGAAAATGGTAAA
ACAAGCTTCGAACCAGCCGATTTAAAAGCACATAGAATGGTAAATGTTATTCTTGATAAAGAAGCGGCTGCAGGTTTACC
TGAAGATGTTAAAGCTTACTTTACGTCACGCTTTGCTTAA
ATGGCAATGAACTTTAAAGTCTTTGACAATAGTCAACTTGTAGCAGAATATGCTGCTGATATTATTAGAAAGCAATTTAA
CAATAATCCTACTACAATTGCAGGTTTTCATTTAGATACAGATCAAGCGCCAGTTCTAGATGAATTAAAGAAAAATGTTG
AAAAACATGCTGTTGATTTTAGCCAAATAAATATTTTAGATTATGACGATAAAAAATCATATTTCGAAGGGTTAGGTGTA
CCAGCAGGTCAAGTTTATCCAATTGCTTATGAAAAAGATGCAATCGAATTAATCGCTGATAAGATTAAAACTAAAGAAAA
TAAAGGGAAATTAACATTACAAGTTGTTTCTATCGATGAGCAAGGTAAGTTAAATGTTAGTATTCGTCAAGGACTAATGG
AAGCAAGAGAAATTTTCTTAGTAGTGACAGGTGCTAATAAACGAGATGTAGTTGAAAAATTATATCAAGAAAATGGTAAA
ACAAGCTTCGAACCAGCCGATTTAAAAGCACATAGAATGGTAAATGTTATTCTTGATAAAGAAGCGGCTGCAGGTTTACC
TGAAGATGTTAAAGCTTACTTTACGTCACGCTTTGCTTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|