Detailed information of TA system TA145479

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mqsRA (relBE)/MqsR-MqsA
• Location: 1472499..1473205
• Replicon: chromosome
• Accession: NZ_CP047134
• Organism: Xylella fastidiosa subsp. multiplex strain IVIA5901

Toxin (Protein)

• Gene name: mqsR
• Uniprot ID: -
• Locus tag: DVT08_RS06680
• Protein ID: WP_128283742.1
• Coordinates: 1472903..1473205 (-)
• Length: 101 a.a.

Antitoxin (Protein)

• Gene name: mqsA
• Uniprot ID: -
• Locus tag: DVT08_RS06675
• Protein ID: WP_060872143.1
• Coordinates: 1472499..1472900 (-)
• Length: 134 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DVT08_RS06645	1468335..1470209	+	1875	WP_004085158.1	phage major capsid protein	-
DVT08_RS06650	1470227..1470487	+	261	WP_128283778.1	hypothetical protein	-
DVT08_RS06655	1470487..1470810	+	324	WP_128382968.1	hypothetical protein	-
DVT08_RS06660	1470807..1471328	+	522	WP_128283721.1	hypothetical protein	-
DVT08_RS06665	1471304..1471846	+	543	WP_128382967.1	hypothetical protein	-
DVT08_RS06670	1471843..1472430	+	588	WP_042836490.1	phage baseplate assembly protein V	-
DVT08_RS06675	1472499..1472900	-	402	WP_060872143.1	type II toxin-antitoxin system MqsA family antitoxin	Antitoxin
DVT08_RS06680	1472903..1473205	-	303	WP_128283742.1	type II toxin-antitoxin system MqsR family toxin	Toxin
DVT08_RS06685	1473434..1473772	+	339	WP_004085176.1	GPW/gp25 family protein	-
DVT08_RS06690	1473772..1474665	+	894	WP_020852318.1	baseplate J/gp47 family protein	-
DVT08_RS06695	1474658..1475214	+	557	Protein_1300	phage tail protein I	-
DVT08_RS06700	1475222..1476814	+	1593	WP_187120391.1	tail fiber domain-containing protein	-
DVT08_RS06705	1476878..1478056	+	1179	WP_187120392.1	phage tail sheath family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1442755..1489908	47153

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase toxin MqsR (2-99)

Antitoxin

• Cro/C1-type helix-turn-helix domain (74-127)

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 10958.74 Da
• Isoelectric Point: 8.0251

>T145479 WP_128283742.1 NZ_CP047134:c1473205-1472903 [Xylella fastidiosa subsp. multiplex]
MEKGTPHYKLPVVKALVKAGKVRATATAYQGARELGIKDLTGMCAVVLALTSADFYKSMTTYTDHTVFQDVYHAKTASGD
EVYLKLTVIDDVLIVSFKEL

Nucleotide

• Length: 303 bp

>T145479 NZ_CP062393:122579-122731 [Staphylococcus aureus]
ATGTCTAAAGACAAAGATCCAAAATTAAATTATCATGAAGAAGAAAACAGTATGGTAACGGATTTTGAAGATTTAAAAGA
ATTAGGTAAAGAAATGGAACAAATCTCTGATCAAAATGATCAAGAAAAGAATTCTGAAGAAGACAGTCAGTAA

Antitoxin

Protein

• Length: 134 a.a.
• Molecular weight: 15004.12 Da
• Isoelectric Point: 7.1650

>AT145479 WP_060872143.1 NZ_CP047134:c1472900-1472499 [Xylella fastidiosa subsp. multiplex]
MRCPCCGAAELIHDTRDMLYTYKSETTSIPTVTGDFCPACGEVVLDREHGDRYSELVGLFQRQVNSAYVDPGYITKVRRK
LDLDQRQAAELFGGGVNAFSRYENGKTKPPLSLVKLFKLLDRHPDLLNEVKSF

Nucleotide

• Length: 402 bp

>AT145479 NZ_CP062393:121955-122554 [Staphylococcus aureus]
ATGGCAATGAACTTTAAAGTCTTTGACAATAGTCAACTTGTAGCAGAATATGCTGCTGATATTATTAGAAAGCAATTTAA
CAATAATCCTACTACAATTGCAGGTTTTCATTTAGATACAGATCAAGTGCCAGTTCTAGATGAATTAAAGAAAAATGTTG
AAAAACATGCTGTTGATTTTAGCCAAATAAATATTTTAGATTATGACGATAAAAAATCATATTTCGAAGCGTTAGGTGTA
CCAGCAGGTCAAGTTTATCCAATTGCTTATGAAAAAGATGCAATCGAATTAATCGCTGATAAGATTAAAACTAAAGAAAA
TAAAGGGAAATTAACATTACAAGTTGTTTCTATCGATGAGCAAGGTAAGTTAAATGTTAGTATTCGTCAAGGACTAATGG
AAGCAAGAGAAATTTTCTTAGTAGTGACAGGTGCTAATAAACGAGATGTAGTTGAAAAATTATATCAAGAAAATGGTAAA
ACAAGCTTCGAACCAGCCGATTTAAAAGCACATAGAATGGTAAATGTTATTCTTGATAAAGAAGCGGCTGCAGGTTTACC
TGAAGATGTTAAAGCTTACTTTACGTCACGCTTTGCTTAA