Detailed information of TA system TA145357

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-RelB
• Location: 3221304..3221813
• Replicon: chromosome
• Accession: NZ_CP047026
• Organism: Polaribacter sp. L3A8

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: GQR92_RS13155
• Protein ID: WP_158840267.1
• Coordinates: 3221553..3221813 (+)
• Length: 87 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: GQR92_RS13150
• Protein ID: WP_158840265.1
• Coordinates: 3221304..3221552 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GQR92_RS13130	3217008..3217673	-	666	WP_158840257.1	LysE family transporter	-
GQR92_RS13135	3217769..3218815	-	1047	WP_158840259.1	ferredoxin--NADP reductase	-
GQR92_RS13140	3218830..3219819	-	990	WP_158840261.1	aspartate-semialdehyde dehydrogenase	-
GQR92_RS13145	3220227..3221258	+	1032	WP_158840263.1	rhodanese-related sulfurtransferase	-
GQR92_RS13150	3221304..3221552	+	249	WP_158840265.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
GQR92_RS13155	3221553..3221813	+	261	WP_158840267.1	Txe/YoeB family addiction module toxin	Toxin
GQR92_RS13160	3222189..3223727	+	1539	WP_158840269.1	hypothetical protein	-
GQR92_RS13165	3223702..3224196	+	495	WP_158840271.1	gliding motility lipoprotein GldH	-
GQR92_RS13170	3224268..3226535	+	2268	WP_158840273.1	transglycosylase domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (1-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-71)

Sequences

Toxin

Protein

• Length: 87 a.a.
• Molecular weight: 10249.89 Da
• Isoelectric Point: 9.7726

>T145357 WP_158840267.1 NZ_CP047026:3221553-3221813 [Polaribacter sp. L3A8]
MKLIWSTSSWNDYIYWQKVDKKIVKRINELIKNCIRAPLEGIGKPEALKGDLQGYWSRRITSEHRLVYKYENEQLLIAAC
SYHYGK

Nucleotide

• Length: 261 bp

>T145357 NZ_CP062364:836381-836701 [Staphylococcus aureus]
ATGAATTGGGAAATTAAAGATTTAATGTGTGACATTGAAGTGATAAAACAAAAAATTAATGATGTAGCTACCAAACATGC
TTGGTTTGTTGAAGATAGATTTGTAAAAAATGAATTAGAAACAAAACGGGAACATATTAATTTTTCTGCTAGCTATTTAG
AACATCGTATACAAAATGAACATACAGTTGAGTTATTACATGTGTACTTAAAAGAATTCAGTGAACTTATACAAAAATTT
CGTGAAATAGAAAAAGCGTCATCAGAGAACTTTGACGAGGAATCAGATGACGCAAAGAATTCAATAAAAGTAGCAGAGTA
A

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9464.75 Da
• Isoelectric Point: 4.8232

>AT145357 WP_158840265.1 NZ_CP047026:3221304-3221552 [Polaribacter sp. L3A8]
METVNYTDFRSNLKHWFDKVFNDVSDIVIKRKGGKDLVLISLDEYNSLKETTYLLTGKNRDVLLNSLKELEAGNGIEKEI
ID

Nucleotide

• Length: 249 bp

>AT145357 NZ_CP062364:836169-836378 [Staphylococcus aureus]
ATGAATAATGAACAAAAAGAAGTAATAGAACACTTGGTTTATCAACTTGAGTTAAGTGTCATGAATAATTTGGAAAGTTA
CGAACACACAGAATATGTTAATGGTATTGAAGTGGTTTCAGAGATCAGTCGTGAAAAGCACTTAGAATTGATAATGAAAT
GGTGCGCACAAGAATTAAAGAATAATTTTCAATTAGAGAAAGGAGAATAA