Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2196384..2196600 Replicon chromosome
Accession NZ_CP047021
Organism Staphylococcus aureus strain M2024

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag GQX63_RS10905 Protein ID WP_001802298.1
Coordinates 2196496..2196600 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2196384..2196439 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GQX63_RS10885 2192521..2193186 - 666 WP_045177733.1 SDR family oxidoreductase -
GQX63_RS10890 2193338..2193658 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
GQX63_RS10895 2193660..2194640 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
GQX63_RS10900 2194906..2195997 + 1092 WP_045177732.1 lytic regulatory protein -
- 2196384..2196439 + 56 - - Antitoxin
GQX63_RS10905 2196496..2196600 - 105 WP_001802298.1 hypothetical protein Toxin
GQX63_RS10910 2197280..2197438 + 159 WP_001792784.1 hypothetical protein -
GQX63_RS10915 2198097..2198954 - 858 WP_045177730.1 Cof-type HAD-IIB family hydrolase -
GQX63_RS10920 2199021..2199803 - 783 WP_045177727.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T145346 WP_001802298.1 NZ_CP047021:c2196600-2196496 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T145346 NZ_CP062362:129714-129866 [Staphylococcus aureus]
ATGTCTAAAGACAAAGATCCAAAATTAAATTATCATGAAGAAGAAAACAGTATGGTAACGGATTTTGAAGATTTAAAAGA
ATTAGGTAAAGAAATGGAACAAATTTCTGATCAAAATGATCAAGAAAAGAATTCTGAAGAAGACAGTCAGTAA

Antitoxin


Download         Length: 56 bp

>AT145346 NZ_CP047021:2196384-2196439 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References