Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 3064863..3065518 Replicon chromosome
Accession NZ_CP046913
Organism Paraburkholderia acidisoli strain DHF22

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag FAZ98_RS13615 Protein ID WP_158951683.1
Coordinates 3064863..3065207 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag FAZ98_RS13620 Protein ID WP_158951684.1
Coordinates 3065204..3065518 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FAZ98_RS13595 3059926..3060246 - 321 WP_158951681.1 DUF1778 domain-containing protein -
FAZ98_RS13600 3060422..3061153 - 732 WP_158951987.1 RNA polymerase sigma factor FliA -
FAZ98_RS13605 3061601..3062395 - 795 Protein_2661 MinD/ParA family protein -
FAZ98_RS13610 3062388..3064433 - 2046 WP_158951682.1 flagellar biosynthesis protein FlhF -
FAZ98_RS13615 3064863..3065207 + 345 WP_158951683.1 toxin Toxin
FAZ98_RS13620 3065204..3065518 + 315 WP_158951684.1 helix-turn-helix domain-containing protein Antitoxin
FAZ98_RS13625 3065593..3067695 - 2103 WP_158951685.1 flagellar biosynthesis protein FlhA -
FAZ98_RS13630 3067692..3068987 - 1296 WP_158951686.1 flagellar type III secretion system protein FlhB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(42-92)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13560.58 Da        Isoelectric Point: 10.1521

>T145152 WP_158951683.1 NZ_CP046913:3064863-3065207 [Paraburkholderia acidisoli]
MNALFVELSLFRERRAAYLDDEAYRALQNELLANPEKGDLIRHTHGLRKVRWKDARRGKGKRGGLRVIYYHWVGGAQFWM
FFVYDKDEVEDLNQQEAKALGVMLRREMEMRTGR

Download         Length: 345 bp

>T145152 NZ_CP062322:1175650-1176111 [Staphylococcus aureus]
ATGGGATTATATGAAGAAACTTTAATACAACATGATTATATTGAAATAAGAGAGGCTGATGTGCTTCCAGATAATTTAGA
CGGGGTATGGTTAGGAGATTTAATTTTGATAAAGCGTGGTTTATCAGATAGAGAAAAAGCAGGAATTCTCTTCGAAGAAT
TAGCGCATAATAAACTTACATACGGTGATATAGCCGATTACTCGAATTTCAACAATCGCAAGTTCGAAAATTACGCACGT
AGACACGGCTTTATCTCAGCAGTCCCGTTACGCGAAATTGTGGAAGCGCACAATTACGGTGTACGTAACTTGTATGAGTT
GTCTGAGTATCTACAATTAAGTGAAGAATACATATTAGAAGCAATAGAACAATACAAAAAGATATATGGTATTGGAACTC
ACTATGGCGAGTATTCTATTACATTTGAGCCGTTGAGAGTTTTTAAATATAAAGAAATATAA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11705.55 Da        Isoelectric Point: 8.7259

>AT145152 WP_158951684.1 NZ_CP046913:3065204-3065518 [Paraburkholderia acidisoli]
MKKARLFDALKQGLDELAAEREGKLTLHTVTLEAPEPLDVTADEIRSVREAVNVSQAVMARRLRVNVRTWQNWEQGKAKP
NAQAAVLIKLVEKHPQTLELLEAL

Download         Length: 315 bp

>AT145152 NZ_CP062322:1175323-1175637 [Staphylococcus aureus]
ATGTGCTTTTCAAAAAGAATGAAACAATCAAGAGAAAAACAAGGTATGACTTTGGCCGAACTAGGAAGAAAAATTGGTAA
AACTGAAGCTACTGTACAACGTTATGAAAGCGGAAATATCAAAAATCTAAAAAACGATACTATAGAAAGTATAGCTACTG
CATTAAATGTTAATCCTGCGTATTTAATGGGGTGGGTTGAAGAAAACGATGATGAAGTACAACATCGTGCAGCTCATTTA
GAAGGAGAATTAACTGATGACGAGTGGCAAAGAGTTTTAGATTATGCAGATTATATAAGAAGTAAACGTAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References