Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 1175818..1176328 Replicon chromosome
Accession NZ_CP046751
Organism Photobacterium damselae strain 9046-81

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag GPX90_RS04845 Protein ID WP_086368444.1
Coordinates 1175818..1176078 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag GPX90_RS04850 Protein ID WP_158134657.1
Coordinates 1176068..1176328 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GPX90_RS04825 1171668..1173245 + 1578 WP_158134656.1 DNA cytosine methyltransferase -
GPX90_RS04830 1173304..1174452 - 1149 WP_086368441.1 iron-containing alcohol dehydrogenase -
GPX90_RS04835 1174612..1175496 + 885 WP_065171313.1 AraC family transcriptional regulator -
GPX90_RS04840 1175508..1175762 + 255 WP_068968730.1 hypothetical protein -
GPX90_RS04845 1175818..1176078 - 261 WP_086368444.1 Txe/YoeB family addiction module toxin Toxin
GPX90_RS04850 1176068..1176328 - 261 WP_158134657.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
GPX90_RS04855 1176521..1178203 - 1683 WP_158134742.1 RluA family pseudouridine synthase -
GPX90_RS04860 1178278..1179012 - 735 WP_115426448.1 hypothetical protein -
GPX90_RS04865 1179019..1179237 - 219 WP_050787827.1 YgjV family protein -
GPX90_RS04870 1179416..1180033 - 618 WP_158134658.1 TPM domain-containing protein -
GPX90_RS04875 1180036..1180791 - 756 WP_068968727.1 TPM domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10318.87 Da        Isoelectric Point: 9.9416

>T144907 WP_086368444.1 NZ_CP046751:c1176078-1175818 [Photobacterium damselae]
MMINFTPNAWDDYLYWQSQDKKTLKRINKLIENCVRTPFEGIGKPEPLKDNLSGYWSRRIDDTHRLVYKATQNTLVIVAV
RFHYQK

Download         Length: 261 bp

>T144907 NZ_CP062245:3270695-3271159 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTCTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAACCCTCACCCGAGAAACAGAAGAAACCCATTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9717.90 Da        Isoelectric Point: 4.4192

>AT144907 WP_158134657.1 NZ_CP046751:c1176328-1176068 [Photobacterium damselae]
MTVLSFSEVRGNFKKVCDQVVDDCDAVVIHRRNADNVVLMSESEFNSWKETMYLMSNPVNAANLLESIKQAECGNVQTHE
LLSHDD

Download         Length: 261 bp

>AT144907 NZ_CP062245:3270360-3270695 [Escherichia coli]
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCAGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTATTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References