Detailed information of TA system TA144555

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2087533..2087848
• Replicon: chromosome
• Accession: NZ_CP046592
• Organism: Bacillus subtilis strain TR21

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: GO005_RS10445
• Protein ID: WP_120322743.1
• Coordinates: 2087533..2087694 (+)
• Length: 54 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2087675..2087848 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GO005_RS10430	2082761..2083096	+	336	WP_009967409.1	hypothetical protein	-
GO005_RS10435	2083143..2086748	-	3606	WP_032721999.1	membrane protein	-
GO005_RS10440	2086981..2087313	-	333	WP_026009814.1	hypothetical protein	-
GO005_RS10445	2087533..2087694	+	162	WP_120322743.1	putative holin-like toxin	Toxin
-	2087675..2087848	-	174	-	-	Antitoxin
GO005_RS10450	2087963..2088805	-	843	WP_003231327.1	hypothetical protein	-
GO005_RS10455	2089005..2089463	-	459	WP_003231326.1	type II toxin-antitoxin system antitoxin YobK	-
GO005_RS10460	2089473..2091275	-	1803	WP_004399481.1	type II toxin-antitoxin system toxin ribonuclease YobL	-
GO005_RS10465	2091377..2091934	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2073599..2097265	23666

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (24-47)

Sequences

Toxin

Protein

• Length: 54 a.a.
• Molecular weight: 5780.74 Da
• Isoelectric Point: 4.6641

>T144555 WP_120322743.1 NZ_CP046592:2087533-2087694 [Bacillus subtilis]
ISCTVSFAHSRESCSSPNERGDAMSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 162 bp

>T144555 NZ_CP062156:c3658301-3658167 [Stenotrophomonas sp. CW117]
ATGAAGCGCACGGTTGCCCTGATGATGCTGTCGTTGTTCTCGATCGCGGTGCTGTCCGGCTGCAATACCGTTGCCGGTGC
CGGCAAGGACGTGCAGAAGGCCGGCGAGAAGGTGGAGGACGCAGCCAAGCGCTGA

Antitoxin

Nucleotide

• Length: 174 bp

>AT144555 NZ_CP046592:c2087848-2087675 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin