Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 46136..46637 Replicon plasmid unnamed1
Accession NZ_CP046581
Organism Erwinia sp. E602

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag GKQ23_RS00185 Protein ID WP_212408280.1
Coordinates 46362..46637 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag GKQ23_RS00180 Protein ID WP_212408279.1
Coordinates 46136..46381 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GKQ23_RS00155 (GKQ23_00155) 41617..42513 + 897 WP_212408277.1 maltose operon protein MalM -
GKQ23_RS00160 (GKQ23_00160) 42692..43015 - 324 WP_056237207.1 hypothetical protein -
GKQ23_RS00165 (GKQ23_00165) 43015..43266 - 252 WP_056237204.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
GKQ23_RS00170 (GKQ23_00175) 43700..44461 - 762 WP_101505016.1 DNA-binding transcriptional regulator YciT -
GKQ23_RS00175 (GKQ23_00180) 44565..45824 - 1260 WP_212408278.1 DUF1479 domain-containing protein -
GKQ23_RS00180 (GKQ23_00185) 46136..46381 + 246 WP_212408279.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
GKQ23_RS00185 (GKQ23_00190) 46362..46637 + 276 WP_212408280.1 Txe/YoeB family addiction module toxin Toxin
GKQ23_RS00190 (GKQ23_00195) 46864..47097 + 234 WP_056238460.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - acrB 1..325969 325969


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10854.32 Da        Isoelectric Point: 10.1716

>T144521 WP_212408280.1 NZ_CP046581:46362-46637 [Erwinia sp. E602]
MSKWNIKFTKNGADDINYWRDTDKKKFERIRQLLHSIEADPLAGIGKPERLRHHKDPALYSRRIDQSHRLVYSIQNGEVI
IYAARYHYGDK

Download         Length: 276 bp

>T144521 NZ_CP062122:c2264265-2264083 [Pseudomonas sp. ADPe]
ATGCGCAGTCGAGAAATCATGGAGTTGATCCGGGCGGATGGCTGGTTCCTGGTGGAGGTGAAAGGCAGTCATCACCAGTT
CCGGCATTTCACCAAGCAGGGGCGGGTGACGGTTCCCCACCCCAGGAGCAACCTGCCGATCGGGACCGTGAACAGTATTC
TGCGCCAGGCCGGCCTGCGATGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9336.38 Da        Isoelectric Point: 4.1953

>AT144521 WP_212408279.1 NZ_CP046581:46136-46381 [Erwinia sp. E602]
MHAINFTDARKNFADTMQRVTDDAEPVRVIRRDAPDVVIMDAEEYEALIETVYLFSNPTNAAHINESMKQAERGEFVEVE
Y

Download         Length: 246 bp

>AT144521 NZ_CP062122:c2264050-2263646 [Pseudomonas sp. ADPe]
ATGAAATTCCCCGTGGTTCTGCACAAGGACGCCGACTCGGATTACGGCGTGACCATCCCTGACGTGCCTGGCTGCTTCTC
CGCCGGCGGCACCGTCAGCCAGGCGCTGGAAAACGTCCAGGAAGCCCTGGCCCTACACTTCGAAGGCCTGGTGGCCGACG
GCGAGACGCTCCCGCAAGCCCAGGAAGTGGACACCCACATGGGCAACCCCGACTACGCCGGCGGCGTCTGGGCGGTGGTC
GACTTCGACGTCACCCCCTACCTGGGCAAGGCCGTGCGCTTCAACGCCAGCCTCCCGGAAAACCTCCTGCAACGCATCGA
CGAACGCGTGAAGCGCGACCATCGCTACGCCTCTCGCTCCGGCTTCCTGGCTACCGCCGCGCTGCGTGAGTTGTCTTCGA
ACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References