Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_37
Location 610032..610675 Replicon chromosome
Accession NZ_CP046444
Organism Granulicella sp. 5B5

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag GOB94_RS02690 Protein ID WP_182277387.1
Coordinates 610032..610355 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag GOB94_RS02695 Protein ID WP_182277388.1
Coordinates 610352..610675 (+) Length 108 a.a.

Genomic Context

GOB94_RS02660GOB94_RS02665GOB94_RS02670GOB94_RS02690GOB94_RS02695GOB94_RS02705GOB94_RS02675GOB94_RS02680GOB94_RS02685GOB94_RS02700
Location: 605196..605873 (678 bp)
Type: Others
Protein ID: WP_182277383.1
Location: 605994..607430 (1437 bp)
Type: Others
Protein ID: WP_182277384.1
Location: 607601..608251 (651 bp)
Type: Others
Protein ID: WP_182277385.1
Location: 610032..610355 (324 bp)
Type: Toxin
Protein ID: WP_182277387.1
Location: 610352..610675 (324 bp)
Type: Antitoxin
Protein ID: WP_182277388.1
Location: 613491..615107 (1617 bp)
Type: Others
Protein ID: WP_182277390.1
Location: 608474..608641 (168 bp)
Type: Others
Protein ID: WP_182277386.1
Location: 608686..609042 (357 bp)
Type: Others
Protein ID: WP_182278389.1
Location: 609064..609651 (588 bp)
Type: Others
Protein ID: WP_182278390.1
Location: 611573..613246 (1674 bp)
Type: Others
Protein ID: WP_182277389.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GOB94_RS02660605196..605873+678WP_182277383.1hypothetical protein-
GOB94_RS02665605994..607430+1437WP_182277384.1hypothetical protein-
GOB94_RS02670607601..608251+651WP_182277385.1DinB family protein-
GOB94_RS02675608474..608641-168WP_182277386.1hypothetical protein-
GOB94_RS02680608686..609042-357WP_182278389.1hypothetical protein-
GOB94_RS02685609064..609651-588WP_182278390.1sigma-70 family RNA polymerase sigma factor-
GOB94_RS02690610032..610355+324WP_182277387.1type II toxin-antitoxin system RelE/ParE family toxinToxin
GOB94_RS02695610352..610675+324WP_182277388.1helix-turn-helix domain-containing proteinAntitoxin
GOB94_RS02700611573..613246-1674WP_182277389.1FAD-dependent oxidoreductase-
GOB94_RS02705613491..615107+1617WP_182277390.1B12-binding domain-containing radical SAM protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--599804..61067510871


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(16-104)

Antitoxin

Cro/C1-type helix-turn-helix domain

(39-85)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12542.75 Da        Isoelectric Point: 10.4037

>T144264 WP_182277387.1 NZ_CP046444:610032-610355 [Granulicella sp. 5B5]
MSWIVEFLDEDVKVLFDSLPLDMRAHFQRIVELIQSHGLERVREPYVKHLEGALWEMRMKGRSGIARAVYVTAIGKRIVV
VHVFTKKTQKTPRREIETALKRAKEVE

Download         Length: 324 bp

>T144264 NZ_CP061801:c2687955-2687851 [Enterobacter mori]
GGCAAGGCGATTTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATA
CAGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 12073.84 Da        Isoelectric Point: 10.9913

>AT144264 WP_182277388.1 NZ_CP046444:610352-610675 [Granulicella sp. 5B5]
MKRKFIPVEDSFAQWKKDPKYAAAYDALEEEFAFASSLIKARTAADMTQAQVAEAMGTTQAVVARLESGRVRPSTRTLER
FAKATHSRLRIIFEPQVRPARSRANTK

Download         Length: 324 bp

>AT144264 NZ_CP061801:2687846-2687990 [Enterobacter mori]
CAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTT
GGCATTAATGCAGGCTAAAATCGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References