Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 1025503..1026005 Replicon chromosome
Accession NZ_CP046377
Organism Pectobacterium polaris strain PZ1

Toxin (Protein)


Gene name yoeB Uniprot ID A0A6P1S0U5
Locus tag GMX10_RS04825 Protein ID WP_039482019.1
Coordinates 1025751..1026005 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A7W2E625
Locus tag GMX10_RS04820 Protein ID WP_039324900.1
Coordinates 1025503..1025754 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GMX10_RS04805 1021903..1022862 + 960 WP_039512800.1 ABC transporter permease -
GMX10_RS04810 1022855..1023721 + 867 WP_039482013.1 ABC transporter permease -
GMX10_RS04815 1023718..1025427 + 1710 WP_161546681.1 ABC transporter ATP-binding protein -
GMX10_RS04820 1025503..1025754 + 252 WP_039324900.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
GMX10_RS04825 1025751..1026005 + 255 WP_039482019.1 Txe/YoeB family addiction module toxin Toxin
GMX10_RS04830 1026047..1026901 - 855 WP_039482022.1 helix-turn-helix domain-containing protein -
GMX10_RS04835 1026926..1027765 - 840 WP_039482025.1 HTH-type transcriptional activator RhaS -
GMX10_RS04840 1028101..1029591 + 1491 WP_161546682.1 rhamnulokinase -
GMX10_RS04845 1029588..1030850 + 1263 WP_014913996.1 L-rhamnose isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10211.76 Da        Isoelectric Point: 8.0353

>T144110 WP_039482019.1 NZ_CP046377:1025751-1026005 [Pectobacterium polaris]
VKLIWSEEAWEDYLYWQDIDKRIVKKINELIKETRRTPFEGKGKPEPLKHNLAGFWSRRITEEHRLVYAITDDAMMIAAC
RYHY

Download         Length: 255 bp

>T144110 NZ_CP061746:c268597-268310 [Enterobacter hormaechei]
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9367.64 Da        Isoelectric Point: 4.6119

>AT144110 WP_039324900.1 NZ_CP046377:1025503-1025754 [Pectobacterium polaris]
MRTISYSEARQNLSATMMKTVEDRAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANAKRLMNSIESLKAGNGEERD
IIE

Download         Length: 252 bp

>AT144110 NZ_CP061746:c268836-268597 [Enterobacter hormaechei]
ATGGGTAGCATTAACCTACGTATTGACGATGAACTTAAAGCGCGTTCTTACGCCGCGCTTGAAAAAATGGGCGTAACTCC
TTCTGAAGCGCTTCGTCTCATGCTCGAGTATATCGCTGACAATGAACGCTTGCCGTTCAAACAGACACTCCTGAGTGATG
AAGATGCTGAACTTGTGGAGATAGTGAAAGAACGACTTCGTAATCCTAAGCCAGTACGTGTGACGCTGGATGAACTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6P1S0U5

Antitoxin

Source ID Structure
AlphaFold DB A0A7W2E625

References