Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yefM-yoeB (relBE)/YoeB-YefM |
Location | 1025503..1026005 | Replicon | chromosome |
Accession | NZ_CP046377 | ||
Organism | Pectobacterium polaris strain PZ1 |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | A0A6P1S0U5 |
Locus tag | GMX10_RS04825 | Protein ID | WP_039482019.1 |
Coordinates | 1025751..1026005 (+) | Length | 85 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | A0A7W2E625 |
Locus tag | GMX10_RS04820 | Protein ID | WP_039324900.1 |
Coordinates | 1025503..1025754 (+) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
GMX10_RS04805 | 1021903..1022862 | + | 960 | WP_039512800.1 | ABC transporter permease | - |
GMX10_RS04810 | 1022855..1023721 | + | 867 | WP_039482013.1 | ABC transporter permease | - |
GMX10_RS04815 | 1023718..1025427 | + | 1710 | WP_161546681.1 | ABC transporter ATP-binding protein | - |
GMX10_RS04820 | 1025503..1025754 | + | 252 | WP_039324900.1 | YoeB-YefM toxin-antitoxin system antitoxin YefM | Antitoxin |
GMX10_RS04825 | 1025751..1026005 | + | 255 | WP_039482019.1 | Txe/YoeB family addiction module toxin | Toxin |
GMX10_RS04830 | 1026047..1026901 | - | 855 | WP_039482022.1 | helix-turn-helix domain-containing protein | - |
GMX10_RS04835 | 1026926..1027765 | - | 840 | WP_039482025.1 | HTH-type transcriptional activator RhaS | - |
GMX10_RS04840 | 1028101..1029591 | + | 1491 | WP_161546682.1 | rhamnulokinase | - |
GMX10_RS04845 | 1029588..1030850 | + | 1263 | WP_014913996.1 | L-rhamnose isomerase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 85 a.a. Molecular weight: 10211.76 Da Isoelectric Point: 8.0353
>T144110 WP_039482019.1 NZ_CP046377:1025751-1026005 [Pectobacterium polaris]
VKLIWSEEAWEDYLYWQDIDKRIVKKINELIKETRRTPFEGKGKPEPLKHNLAGFWSRRITEEHRLVYAITDDAMMIAAC
RYHY
VKLIWSEEAWEDYLYWQDIDKRIVKKINELIKETRRTPFEGKGKPEPLKHNLAGFWSRRITEEHRLVYAITDDAMMIAAC
RYHY
Download Length: 255 bp
>T144110 NZ_CP061746:c268597-268310 [Enterobacter hormaechei]
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9367.64 Da Isoelectric Point: 4.6119
>AT144110 WP_039324900.1 NZ_CP046377:1025503-1025754 [Pectobacterium polaris]
MRTISYSEARQNLSATMMKTVEDRAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANAKRLMNSIESLKAGNGEERD
IIE
MRTISYSEARQNLSATMMKTVEDRAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANAKRLMNSIESLKAGNGEERD
IIE
Download Length: 252 bp
>AT144110 NZ_CP061746:c268836-268597 [Enterobacter hormaechei]
ATGGGTAGCATTAACCTACGTATTGACGATGAACTTAAAGCGCGTTCTTACGCCGCGCTTGAAAAAATGGGCGTAACTCC
TTCTGAAGCGCTTCGTCTCATGCTCGAGTATATCGCTGACAATGAACGCTTGCCGTTCAAACAGACACTCCTGAGTGATG
AAGATGCTGAACTTGTGGAGATAGTGAAAGAACGACTTCGTAATCCTAAGCCAGTACGTGTGACGCTGGATGAACTCTGA
ATGGGTAGCATTAACCTACGTATTGACGATGAACTTAAAGCGCGTTCTTACGCCGCGCTTGAAAAAATGGGCGTAACTCC
TTCTGAAGCGCTTCGTCTCATGCTCGAGTATATCGCTGACAATGAACGCTTGCCGTTCAAACAGACACTCCTGAGTGATG
AAGATGCTGAACTTGTGGAGATAGTGAAAGAACGACTTCGTAATCCTAAGCCAGTACGTGTGACGCTGGATGAACTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A6P1S0U5 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7W2E625 |