Detailed information of TA system TA143720

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 96499..96694
• Replicon: chromosome
• Accession: NZ_CP046247
• Organism: Enterococcus faecalis strain RF_1_1_25_1

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: GLO19_RS00550
• Protein ID: WP_015543884.1
• Coordinates: 96599..96694 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	96499..96564 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GLO19_RS00535	92130..93872	+	1743	WP_002401739.1	PTS transporter subunit EIIC	-
GLO19_RS00540	93863..95896	+	2034	WP_002355275.1	BglG family transcription antiterminator	-
GLO19_RS00545	95907..96341	+	435	WP_002355276.1	PTS sugar transporter subunit IIA	-
-	96499..96564	+	66	-	-	Antitoxin
GLO19_RS00550	96599..96694	-	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
GLO19_RS00555	96940..98712	+	1773	WP_002391520.1	PTS mannitol-specific transporter subunit IIBC	-
GLO19_RS00560	98727..99164	+	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
GLO19_RS00565	99179..100333	+	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-
GLO19_RS00570	100402..101517	-	1116	WP_002377910.1	FAD-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T143720 WP_015543884.1 NZ_CP046247:c96694-96599 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T143720 NZ_CP061337:c3742200-3741793 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCTGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin

Nucleotide

• Length: 66 bp

>AT143720 NZ_CP046247:96499-96564 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATCAGTAGTAGGGTGTCTTTTTTT

Structures

Antitoxin