Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 4020695..4021197 Replicon chromosome
Accession NZ_CP046155
Organism Leptolyngbya sp. BL0902

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag GFS31_RS17810 Protein ID WP_198806076.1
Coordinates 4020943..4021197 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag GFS31_RS17805 Protein ID WP_198806075.1
Coordinates 4020695..4020946 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GFS31_RS17785 4016267..4017367 - 1101 WP_198806072.1 bifunctional riboflavin kinase/FAD synthetase -
GFS31_RS17790 4017521..4018402 - 882 WP_198806073.1 MBL fold metallo-hydrolase -
GFS31_RS17795 4018594..4020006 - 1413 WP_198806074.1 nucleoside:proton symporter -
GFS31_RS17800 4020245..4020424 - 180 WP_198808302.1 hypothetical protein -
GFS31_RS17805 4020695..4020946 + 252 WP_198806075.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
GFS31_RS17810 4020943..4021197 + 255 WP_198806076.1 Txe/YoeB family addiction module toxin Toxin
GFS31_RS17815 4021306..4021590 - 285 WP_198806077.1 hypothetical protein -
GFS31_RS17820 4021580..4021876 - 297 WP_198806078.1 BrnT family toxin -
GFS31_RS17825 4022242..4023633 + 1392 WP_198808303.1 DNA cytosine methyltransferase -
GFS31_RS17830 4023670..4024470 - 801 WP_198806079.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10156.81 Da        Isoelectric Point: 9.6255

>T143693 WP_198806076.1 NZ_CP046155:4020943-4021197 [Leptolyngbya sp. BL0902]
MKIIFAEAAWEDYLYWQKTDKKMLQRINELIKTAIRTPFEGIGKPEPLKHGLKGYWSRRITDEHRLVYKVQDDSILIAQC
RYHY

Download         Length: 255 bp

>T143693 NZ_CP061329:c2457741-2457565 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9284.43 Da        Isoelectric Point: 4.3440

>AT143693 WP_198806075.1 NZ_CP046155:4020695-4020946 [Leptolyngbya sp. BL0902]
MDAISYTAARQNLAKTMDRVCSDHEPIIITRNNEQSVVMISLEDFNALEETAYLLRSPKNAKRLLESIAQLEASGGTEKE
LDD

Download         Length: 252 bp

>AT143693 NZ_CP061329:c2457519-2457103 [Escherichia coli]
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
GCAGGGCGAAACTGTCGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ACGAGCTTATCCCGTTACCTTCGCCATTAAATAGTCATGATCACTTTATTGAAGTACCTTTGAGCGTCGCCTCTAAAGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGGCGAATTGGCAAACCTAAACAGGAGAT
TACTCGCCTATTTAACTTGCACCATGCGACAAAAATCGACGCCGTCCAGCTTGCGGCAAAGGCGCTTGGCAAAGAGTTAT
CGCTGGTGATGGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References