Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 1799666..1800316 Replicon chromosome
Accession NZ_CP046114
Organism Glaesserella parasuis strain SCW0912

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag GJV39_RS09050 Protein ID WP_021110393.1
Coordinates 1799666..1800004 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag GJV39_RS09055 Protein ID WP_005710405.1
Coordinates 1800008..1800316 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GJV39_RS09015 1794763..1796910 + 2148 WP_021110395.1 cadmium-translocating P-type ATPase -
GJV39_RS09025 1797393..1798832 - 1440 WP_021110394.1 glutamate--tRNA ligase -
GJV39_RS09050 1799666..1800004 + 339 WP_021110393.1 selenocysteine synthase Toxin
GJV39_RS09055 1800008..1800316 + 309 WP_005710405.1 helix-turn-helix domain-containing protein Antitoxin
GJV39_RS09060 1800517..1801677 + 1161 WP_010786053.1 bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN -
GJV39_RS09065 1801777..1802358 + 582 WP_021110392.1 type IV pilus biogenesis/stability protein PilW -
GJV39_RS09070 1802419..1803354 + 936 WP_021110391.1 KpsF/GutQ family sugar-phosphate isomerase -
GJV39_RS09075 1803354..1803833 + 480 WP_021110390.1 transcription elongation factor GreB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-86)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 13302.34 Da        Isoelectric Point: 10.0084

>T143636 WP_021110393.1 NZ_CP046114:1799666-1800004 [Glaesserella parasuis]
MNVTFVELPPFEEYRKKYLDDDTFRLLQNELLKFPDKGELIQGTGGLRKLRIVDIIRQKGKRGGARVIYYYYVRGKQVWL
FHAYNKNQQDDLSNEERVVLANTLSYLKSLVR

Download         Length: 339 bp

>T143636 NZ_CP061297:259085-259573 [Polynucleobacter asymbioticus]
ATGAGTGTGCAGGAAGTTTGGAGAATTGCCCTCGATGCACCCCTATTTAAGGCGGATGATCTTAGTGGGGAGGGTGCAAA
AAAATCCGGTGGCAGATGGAATAAAAAAGGGACACCTGTTTTATATACCTCGGAGTCCATTGCACTTGCTTGTCTAGAAA
CTCTGGTGCATATCAATGCCCAAGGTCTTCCCCTGACCCGCTATCTAGTGCGCATTGATATCCCAACGAGAGTATGGAAT
TTAGCCAAGAGGCTAAATCCTAAAACGGCTGGTGCAGGTTGGGATGCATTGCCAGCGGGGGCTGCCAGTATTGAGAAGGG
GCAGAAATGGCTGCAATCGAATGCAAGTGCTTTGTTGTTCGTGCCTTCAGTAGTTATTCCGCAGGCAAGCAATGTGTTGA
TTAATCCCATGCATCCAGATATCAAGCTGATTAAAGCTAAGAAAATTGAACAATTTTCTTATGACCCACGTTTAGTGGGT
CAGCCTTAA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11539.61 Da        Isoelectric Point: 10.2919

>AT143636 WP_005710405.1 NZ_CP046114:1800008-1800316 [Glaesserella parasuis]
MGKLFNELMEGMQALELHLQGKITLKTTVVEVPDPIVITPEEVKAIRQKLNLSQAVFARKLHTSVRTYQGWEQGRTKPNP
QAVLLLKMVEKSPKTFEQIASI

Download         Length: 309 bp

>AT143636 NZ_CP061297:258588-259088 [Polynucleobacter asymbioticus]
ATGCCCAGCGTAATCCATAAAAAAGCTACGACGAGAGTGCTTCGTAAATCTTCGCTGGAAATTACCCAGCAGGATTTATC
TTTTGCCACTATTTATCGAGTGGAGCCTATGGATCGCATCAAGTTGATTCGAGGTGGAATTCCCGCTAGATATATCAACG
TTATTTCTGATTCCATGGGAATTACAAAAGAAACCTTATTTAAGTTCTTGAATTTGCCGAAGTCGACCATTGACAAGAAG
TCTGTGGCTAACCAAATGCTACCAATTGAGCAGGGTGAGCGTTTGATCGGTATGGCTAAGCTAGTGGGGCAAATAGAGTC
AATCATTGCTGAGTCAGGGAACCCAGATGGTTTCAATGCCGCTAAGTGGATGGCAAGTTGGCTTGAAAAACCCTCCCCAG
CATTAGGTGGTGAGAAGCCGTCAGCCTACCTAGATACAGTTTCTGGTCAAGAAATGATTTCTGATCTCCTTGCCAAAATT
CAAACTGGAGCATACGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References