Detailed information of TA system TA143604

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 309009..309203
• Replicon: chromosome
• Accession: NZ_CP046113
• Organism: Enterococcus faecalis strain 092160007-3

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: GKQ54_RS01545
• Protein ID: WP_015543884.1
• Coordinates: 309108..309203 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	309009..309073 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GKQ54_RS01530	304642..306384	+	1743	WP_002399652.1	PTS transporter subunit EIIC	-
GKQ54_RS01535	306375..308408	+	2034	WP_010777372.1	transcription antiterminator	-
GKQ54_RS01540	308419..308853	+	435	WP_002358391.1	PTS sugar transporter subunit IIA	-
-	309009..309073	+	65	-	-	Antitoxin
GKQ54_RS01545	309108..309203	-	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
GKQ54_RS01550	309449..311221	+	1773	WP_010706745.1	PTS mannitol transporter subunit IICBA	-
GKQ54_RS01555	311236..311673	+	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
GKQ54_RS01560	311688..312842	+	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-
GKQ54_RS01565	312909..314024	-	1116	WP_002379062.1	FAD-binding oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T143604 WP_015543884.1 NZ_CP046113:c309203-309108 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T143604 NZ_CP061285:1582453-1582857 [Polynucleobacter sp. MWH-UH35A]
ATGAACGCTAAGAAAATATTTTTTGATACAAATACCCTACTTTATCTGCTGTCCTCCGATAACAAAAAAGCAGATTGGGT
CAGCAAAAATCTTCAGCATCACAATGTAATTAGCGTTCAAGTGCTCAATGAATTTACTTCAGCAAGCCTTAGAAAAATAA
AAATATCTAACAGTGAGTTAGATGAGTTTTTAGATCTATTTACATCGACATTTCACGTAAGATCTCTAGATATAGATACC
TTTGAGACTGGACTTATGGTTTCCAGAAGATACGGATACCAACACTATGATTCGATGATTATTGCTGCTGCACTCCAAGC
AGGTTGCGAGAGACTTTACTCAGAAGATATGCAGCATCGACAAATTATTGATAAGAGACTTCAAATCGTGAACCCTTTTG
CATAA

Antitoxin

Nucleotide

• Length: 65 bp

>AT143604 NZ_CP046113:309009-309073 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT

Structures

Antitoxin