Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-ratA/- |
Location | 2395192..2395478 | Replicon | chromosome |
Accession | NZ_CP046112 | ||
Organism | Enterococcus faecalis strain 111540027-2 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | - |
Locus tag | GKQ55_RS11540 | Protein ID | WP_002393909.1 |
Coordinates | 2395350..2395478 (-) | Length | 43 a.a. |
Antitoxin (RNA)
Gene name | ratA | ||
Locus tag | - | ||
Coordinates | 2395192..2395401 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
GKQ55_RS11510 | 2390442..2391395 | - | 954 | WP_002404024.1 | siderophore ABC transporter substrate-binding protein | - |
GKQ55_RS11515 | 2391434..2392189 | - | 756 | WP_002354962.1 | ATP-binding cassette domain-containing protein | - |
GKQ55_RS11520 | 2392186..2393151 | - | 966 | WP_002354961.1 | iron chelate uptake ABC transporter family permease subunit | - |
GKQ55_RS11525 | 2393148..2394095 | - | 948 | WP_174776051.1 | iron chelate uptake ABC transporter family permease subunit | - |
GKQ55_RS11530 | 2394280..2394732 | + | 453 | WP_002354958.1 | YueI family protein | - |
- | 2394758..2394968 | + | 211 | NuclAT_4 | - | - |
- | 2394795..2394972 | + | 178 | NuclAT_3 | - | - |
GKQ55_RS11535 | 2394917..2395044 | - | 128 | Protein_2266 | putative holin-like toxin | - |
- | 2395192..2395401 | + | 210 | NuclAT_5 | - | Antitoxin |
- | 2395226..2395405 | + | 180 | NuclAT_2 | - | - |
GKQ55_RS11540 | 2395350..2395478 | - | 129 | WP_002393909.1 | hypothetical protein | Toxin |
GKQ55_RS11545 | 2395641..2397911 | - | 2271 | WP_002354955.1 | bifunctional glutamate--cysteine ligase/glutathione synthetase | - |
GKQ55_RS11550 | 2398082..2398582 | + | 501 | WP_002354954.1 | cysteine hydrolase | - |
GKQ55_RS11555 | 2399129..2400025 | + | 897 | WP_002365354.1 | YitT family protein | - |
GKQ55_RS11560 | 2400076..2400474 | - | 399 | WP_002354951.1 | glyoxalase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 43 a.a. Molecular weight: 4743.64 Da Isoelectric Point: 5.6470
>T143577 WP_002393909.1 NZ_CP046112:c2395478-2395350 [Enterococcus faecalis]
MHFNERSIFLSIEAALELMISFAAFVALLIFGILEATKNDKK
MHFNERSIFLSIEAALELMISFAAFVALLIFGILEATKNDKK
Download Length: 129 bp
>T143577 NZ_CP061206:3987632-3987883 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA
Antitoxin
Download Length: 210 bp
>AT143577 NZ_CP046112:2395192-2395401 [Enterococcus faecalis]
TTCCATTTTAAATAGAATTATGCTATTATGAAAATGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACAC
CAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTT
ATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTAGTGCA
TTCCATTTTAAATAGAATTATGCTATTATGAAAATGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACAC
CAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTT
ATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTAGTGCA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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