Detailed information of TA system TA143574

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 54795..54989
• Replicon: chromosome
• Accession: NZ_CP046112
• Organism: Enterococcus faecalis strain 111540027-2

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: GKQ55_RS00250
• Protein ID: WP_015543884.1
• Coordinates: 54894..54989 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	54795..54859 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GKQ55_RS00235	50419..52167	+	1749	WP_002403688.1	PTS transporter subunit EIIC	-
GKQ55_RS00240	52158..54191	+	2034	WP_002355275.1	transcription antiterminator	-
GKQ55_RS00245	54202..54636	+	435	WP_002355276.1	PTS sugar transporter subunit IIA	-
-	54795..54859	+	65	NuclAT_14	-	Antitoxin
GKQ55_RS00250	54894..54989	-	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
GKQ55_RS00255	55235..57007	+	1773	WP_002387897.1	PTS mannitol transporter subunit IICBA	-
GKQ55_RS00260	57022..57459	+	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
GKQ55_RS00265	57474..58628	+	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T143574 WP_015543884.1 NZ_CP046112:c54989-54894 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T143574 NZ_CP061206:c2940965-2940588 [Escherichia coli]
ATGAAAACATTACCCGACACACACGTACGGGCGGCATCGCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCACTATGGCCTCACGCTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGGATTTCACTGTGTGACGCGGTGAACTTTCTCGTTGAAAAATACGCGCAGGTACGTACCGACCAGCCGGGATTC
AGCGCAGGAGCCCCGTCGCAGTTAATCAACAGCATTGATATTCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCGGAA
CAATTACAGAATGGTAAATAACATTACCCAGGGCAAGCATCCGGAGGCAAAACGATGA

Antitoxin

Nucleotide

• Length: 65 bp

>AT143574 NZ_CP046112:54795-54859 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGCGGTAGGGTGTCTTTTTTT

Structures

Antitoxin