Detailed information of TA system TA143534

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 2749608..2749802
• Replicon: chromosome
• Accession: NZ_CP046108
• Organism: Enterococcus faecalis strain 133170041-3

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: GKQ57_RS13100
• Protein ID: WP_015543884.1
• Coordinates: 2749608..2749703 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	2749738..2749802 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GKQ57_RS13080	2744785..2745900	+	1116	WP_002364956.1	FAD-binding oxidoreductase	-
GKQ57_RS13085	2745969..2747123	-	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-
GKQ57_RS13090	2747138..2747575	-	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
GKQ57_RS13095	2747590..2749362	-	1773	WP_002391520.1	PTS mannitol transporter subunit IICBA	-
GKQ57_RS13100	2749608..2749703	+	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	2749738..2749802	-	65	-	-	Antitoxin
GKQ57_RS13105	2749973..2750407	-	435	WP_002358391.1	PTS sugar transporter subunit IIA	-
GKQ57_RS13110	2750418..2752451	-	2034	WP_002355275.1	transcription antiterminator	-
GKQ57_RS13115	2752442..2754184	-	1743	WP_002391519.1	PTS transporter subunit EIIC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T143534 WP_015543884.1 NZ_CP046108:2749608-2749703 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T143534 NZ_CP061185:c3820370-3819963 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATCCACGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGACGCATTAATGCTCGCCAGGGAGAAATTCGCCTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCGCCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGACAGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin

Nucleotide

• Length: 65 bp

>AT143534 NZ_CP046108:c2749802-2749738 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT

Structures

Antitoxin