Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 1273351..1274174 Replicon chromosome
Accession NZ_CP046058
Organism Microcystis aeruginosa NIES-298

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag D3800_RS05945 Protein ID WP_103111352.1
Coordinates 1273351..1273848 (-) Length 166 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag D3800_RS05950 Protein ID WP_202861573.1
Coordinates 1273851..1274174 (-) Length 108 a.a.

Genomic Context

D3800_RS05930D3800_RS05940D3800_RS05955D3800_RS05935D3800_RS05945D3800_RS05950D3800_RS05960D3800_RS05965D3800_RS05970D3800_RS05975
Location: 1269398..1270423 (1026 bp)
Type: Others
Protein ID: WP_002732998.1
Location: 1272294..1273005 (712 bp)
Type: Others
Protein ID: Protein_1177
Location: 1274444..1275622 (1179 bp)
Type: Others
Protein ID: WP_002732401.1
Location: 1270876..1271733 (858 bp)
Type: Others
Protein ID: WP_162205119.1
Location: 1273351..1273848 (498 bp)
Type: Toxin
Protein ID: WP_103111352.1
Location: 1273851..1274174 (324 bp)
Type: Antitoxin
Protein ID: WP_202861573.1
Location: 1276515..1276982 (468 bp)
Type: Others
Protein ID: WP_103111349.1
Location: 1276960..1277172 (213 bp)
Type: Others
Protein ID: WP_103111367.1
Location: 1277195..1277767 (573 bp)
Type: Others
Protein ID: WP_103111348.1
Location: 1277922..1278755 (834 bp)
Type: Others
Protein ID: WP_103111347.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
D3800_RS059301269398..1270423+1026WP_002732998.1ABC transporter permease-
D3800_RS059351270876..1271733-858WP_162205119.1IS5 family transposase-
D3800_RS059401272294..1273005+712Protein_1177IS1 family transposase-
D3800_RS059451273351..1273848-498WP_103111352.1type II toxin-antitoxin system YhaV family toxinToxin
D3800_RS059501273851..1274174-324WP_202861573.1type II toxin-antitoxin system PrlF family antitoxinAntitoxin
D3800_RS059551274444..1275622+1179WP_002732401.1AI-2E family transporter-
D3800_RS059601276515..1276982-468WP_103111349.1hypothetical protein-
D3800_RS059651276960..1277172-213WP_103111367.1hypothetical protein-
D3800_RS059701277195..1277767-573WP_103111348.1hypothetical protein-
D3800_RS059751277922..1278755-834WP_103111347.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-flankIS/Tn--1270876..1271769893


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(14-151)

Antitoxin

PrlF antitoxin

(6-104)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 19741.31 Da        Isoelectric Point: 7.4613

>T143475 WP_103111352.1 NZ_CP046058:c1273848-1273351 [Microcystis aeruginosa NIES-298]
MSIDQPLVINGWSIFAHPLFLEQFEELVTQVEELRHKFPQDYKRKNATKRLAAIAKLAFDTIPQDPTRSDYRQGTTLGDD
YKHWFRAKFFQQYRLFFRYHQESKIILLAWVNDENSKRAYESSTDAYRVFRKMLETSYPPDDWHDLLKEAKSTISRLREA
AETEI

Download         Length: 498 bp

>T143475 NZ_CP061108:1347611-1348009 [Escherichia coli]
ATGCTGAAATTCATGCTGGATACCAATATCTGTATTTTCACTATTAAGAATAAACCAGTACATGTCAGAGAGCGGTTTAA
CCTGAATTCTGGCCGGATGTGTATAAGTTCTGTAACATTGATGGAGCTTATCTATGGGGCAGAAAAAAGTCAGATGCCAG
AACGCAATTTGGCGGTTATTGAAGGTTTCGTATCTCGTTTGGTAGTGCTTGATTATGATAGTGCTGCTGCGACGCATACC
GGGCAAATCAGGGCCGAGCTTGCCCGGCAGGGAAGGCCTGTTGGACCTTTTGACCAGATGATAGCGGGACATGCTCGCAG
TCGCGGTTTGATTGTGGTTACCAACAATACCCGAGAGTTTGAGCGAGTGGCGGGAATCAGACTAGAAGACTGGAGCTAA

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 12035.48 Da        Isoelectric Point: 4.1961

>AT143475 WP_202861573.1 NZ_CP046058:c1274174-1273851 [Microcystis aeruginosa NIES-298]
MAPWPESTLTDRYQTTIPDSVRKALGLNKRDKICYNIQPDGKVWISRADGTEENDPVLGKFLNFLAQDMEQNPQHIQAIS
SNLVNHVQCLVSGVDLELDAPLLDEDE

Download         Length: 324 bp

>AT143475 NZ_CP061108:1347384-1347611 [Escherichia coli]
ATGGAAACTACTGTATTTTTAAGTAATCGCAGTCAGGCCGTCAGATTACCGAAAGCGGTCGCTCTGCCAGAAGACGTTAA
GAAAGTAGAAATTATTGCGATTGGTCGTACAAGAATCATCACTCCCGCCGGTGAGTCCTGGGACAGTTGGTTTGATGGCG
AAAATGTGAGTGCGGATTTTATGGATATCCGTGATCAACCCGCAATGCAGGAAAGGGAATCATTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References