Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 3119264..3119859 Replicon chromosome
Accession NZ_CP046023
Organism Polaromonas sp. Pch-P

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag F7R28_RS14375 Protein ID WP_122956311.1
Coordinates 3119575..3119859 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag F7R28_RS14370 Protein ID WP_122956312.1
Coordinates 3119264..3119578 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F7R28_RS14345 3114897..3115910 - 1014 WP_122956317.1 sulfate ABC transporter substrate-binding protein -
F7R28_RS14350 3115907..3116506 - 600 WP_122956316.1 alpha/beta hydrolase -
F7R28_RS14355 3116528..3117178 - 651 WP_122956315.1 peroxiredoxin -
F7R28_RS14360 3117391..3118296 - 906 WP_122956314.1 LysR family transcriptional regulator -
F7R28_RS14365 3118498..3119148 + 651 WP_122956313.1 NAD(P)H-dependent oxidoreductase -
F7R28_RS14370 3119264..3119578 - 315 WP_122956312.1 transcriptional regulator Antitoxin
F7R28_RS14375 3119575..3119859 - 285 WP_122956311.1 toxin Toxin
F7R28_RS14380 3120022..3120570 - 549 WP_122956310.1 NAD(P)H-dependent oxidoreductase -
F7R28_RS14385 3120904..3123561 + 2658 WP_194965995.1 excinuclease ABC subunit UvrA -
F7R28_RS14390 3123558..3124352 - 795 WP_122956308.1 MetQ/NlpA family ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(42-101)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10723.26 Da        Isoelectric Point: 9.4855

>T143394 WP_122956311.1 NZ_CP046023:c3119859-3119575 [Polaromonas sp. Pch-P]
MDDEGFRGLQEAMMRNPEAGDAIEGTGGLRKLRHGDPRRGKGKRGGLRVIYYWWDGGSQFWLFTLYDKDEMADLNAGEKK
ALKGMLKMELEAKR

Download         Length: 285 bp

>T143394 NZ_CP061080:c3165733-3165242 [Mesirhizobium sp. NIBR3]
GTGAGCCTGCAGGCCCCCGGACCACTCGGCGAGGCTCATGATTTCGCGGCGTTCGCCTCGGGAGCCGACGGCCTCGACGA
CTGGCTGAAACGGCGTGCGCGCTTCAATCAGGCGAGCGGCGCCTCCCGCACCTATGTCGTCGCGGATGGAACGCGCGTGG
TCGGCTATTGTGCGCTGGCGTCCGGCGCGGTGGTCCTGAGCGCGGCTTCCAGCAGGATCAGCCGCAACATGCCCGACCCA
ATTCCGATCGTCGTGTTCGGCCGCCTCGCGGTCGATCGCGAATGGCAAGGAAGGGGACTGGGCAGCGCCATGTTCCGCGA
CGCTGCGCACCGCGTGCGGCGAGCCGCCGACACCATCGGAATCCGCGGCATGCTCGTTCATGCCATTTCTGAGGACGCGC
GGCAGTTCTACCTGTCGCTCGGCTTCGAGCCGTCGATGCTCGATCCGATGACGCTGTTGGTTCGCCTGGCCGACATCGAG
ACGGCTCGATGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11763.45 Da        Isoelectric Point: 9.9175

>AT143394 WP_122956312.1 NZ_CP046023:c3119578-3119264 [Polaromonas sp. Pch-P]
MKKRNLFAEITEGFDALSNARAGKQTLRTHEVEINPAPDVTADELLALRESLHLSRPVFARYLRTNPRTLENWEQGRAKP
NAQAALLIRLVEKFPDTVDRLAAV

Download         Length: 315 bp

>AT143394 NZ_CP061080:c3166041-3165730 [Mesirhizobium sp. NIBR3]
ATGACGATGCAACCCACATCGAAGCCGACCGAGAAGGTGTCGCGTCCCGTCCGCGACACGCTGAACCTGCGGATTCGGCC
GGACCTGCGCAGCCTGATCGATCAGGCTGCCGAACTCGCCGGCAAGTCCCGCTCCGACTTCGTGCTGGAGGCATCCCGCC
GGGCGGCGGAGGAAACTCTGCGTGATCGCACGCTGTGGCTGGCTGATCCGGACGCCTTCGCAGCCTTCTGCGAAAGGCTC
GATTTGCCATCTGCGCCGAGTGAGAGGCTGCGGCACGTCTTGGCTCGAAAGGCGCCCTGGGAACAGCCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References