Detailed information of TA system TA143370

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 1415908..1416111
• Replicon: chromosome
• Accession: NZ_CP046022
• Organism: Enterococcus faecalis strain BFF1B1

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: GIO26_RS06560
• Protein ID: WP_157734666.1
• Coordinates: 1415908..1416012 (+)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	1416047..1416111 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GIO26_RS06540	1411096..1412211	+	1116	WP_002380024.1	FAD-binding oxidoreductase	-
GIO26_RS06545	1412278..1413432	-	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-
GIO26_RS06550	1413447..1413884	-	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
GIO26_RS06555	1413899..1415671	-	1773	WP_002405272.1	PTS mannitol transporter subunit IICBA	-
GIO26_RS06560	1415908..1416012	+	105	WP_157734666.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	1416047..1416111	-	65	-	-	Antitoxin
GIO26_RS06565	1416282..1416716	-	435	WP_002358391.1	PTS sugar transporter subunit IIA	-
GIO26_RS06570	1416727..1418760	-	2034	WP_002355275.1	transcription antiterminator	-
GIO26_RS06575	1418751..1420499	-	1749	WP_002393697.1	PTS transporter subunit EIIC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 4014.85 Da
• Isoelectric Point: 6.4459

>T143370 WP_157734666.1 NZ_CP046022:1415908-1416012 [Enterococcus faecalis]
VHHIYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 105 bp

>T143370 NZ_CP061072:3340016-3340450 [Streptomyces sp. CB00271]
TTGATCATCGTCGCCGACACCTCGGCCCTCTACGCCGCTTTCGACGCCGCGCAGGCGGAGCACCCGGAGGCGGCCAGGAT
CCTGGAGAACGAACGGCTCGCCATCTCGCCCCTGGTCGTCACCGAGCTGGACCACCTGGTCCATCGCGACCTGGGGTTCC
CAGCGGCCATGCAGGTGATGGAGGCGTTGAATTCCCGTATGGACGACGGGCAGTACCGCCTCGCCGAACTCAGGCTCGCG
GACCTGCGTACCGCCCAGGAAGTCCGGCAGAAGTACGAAGGTCTGCGGCTCGACCTGGCCGACGCGGTCGGAGTGGTCCT
CGCCGACCGCTACCGGACGGACCGCATCTTCACCTTGGACCAACGCGACTTCCGGGCGATGTCACCCCTGACTCCCGGAC
TGGACGCCTTCCGGATCCTGCCCGCCGACGACTGA

Antitoxin

Nucleotide

• Length: 65 bp

>AT143370 NZ_CP046022:c1416111-1416047 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT

Structures

Antitoxin