Detailed information of TA system TA143029

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2113101..2113260
• Replicon: chromosome
• Accession: NZ_CP045927
• Organism: Staphylococcus agnetis strain 1379

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: GJE18_RS10705
• Protein ID: WP_107365594.1
• Coordinates: 2113159..2113260 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2113101..2113134 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GJE18_RS10680	2108933..2110372	-	1440	WP_107368622.1	alkaline phosphatase	-
GJE18_RS10685	2110591..2111241	+	651	WP_107368623.1	zinc ribbon domain-containing protein	-
GJE18_RS10690	2111314..2111928	-	615	WP_060551885.1	DedA family protein	-
GJE18_RS10695	2112046..2112456	-	411	WP_085622846.1	hypothetical protein	-
GJE18_RS10700	2112718..2112990	+	273	WP_103346255.1	DUF2316 family protein	-
-	2113101..2113134	+	34	-	-	Antitoxin
GJE18_RS10705	2113159..2113260	-	102	WP_107365594.1	type I toxin-antitoxin system Fst family toxin	Toxin
GJE18_RS10710	2113395..2114405	-	1011	WP_060551888.1	HoxN/HupN/NixA family nickel/cobalt transporter	-
GJE18_RS10715	2114619..2115296	+	678	WP_037565806.1	response regulator transcription factor	-
GJE18_RS10720	2115289..2116773	+	1485	WP_060551889.1	HAMP domain-containing histidine kinase	-
GJE18_RS10725	2116994..2117434	-	441	WP_060551890.1	antibiotic biosynthesis monooxygenase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3789.56 Da
• Isoelectric Point: 10.7732

>T143029 WP_107365594.1 NZ_CP045927:c2113260-2113159 [Staphylococcus agnetis]
MLDILVHITTTIISGCIVTLFAHWLRTRGNKHK

Nucleotide

• Length: 102 bp

>T143029 NZ_CP060928:c644997-643675 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCAAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCCAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTGACGTTAATACCCGAAGA
CGAAACCGTAACGCATCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGACTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCGCTAGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCACAGGAGAAGACAGCACTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAATTCCAGGTCTTCCAGTGGTTGATTGGCGCAACGGACGGTCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTTTGGCGACAGCAAAGGTGCTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCA
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAAGCAATGTGTT
GAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAGTGA

Antitoxin

Nucleotide

• Length: 34 bp

>AT143029 NZ_CP045927:2113101-2113134 [Staphylococcus agnetis]
CACCAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Antitoxin