Detailed information of TA system TA142729

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-as-bsrH/-
• Location: 2210046..2210263
• Replicon: chromosome
• Accession: NZ_CP045824
• Organism: Bacillus subtilis strain MB8_B10

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: -
• Locus tag: GII78_RS11360
• Protein ID: WP_014470124.1
• Coordinates: 2210046..2210222 (-)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	as-bsrH
Locus tag	-
Coordinates	2210163..2210263 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GII78_RS11315	2205599..2205826	-	228	WP_113712930.1	helix-turn-helix transcriptional regulator	-
GII78_RS11320	2205916..2206358	-	443	Protein_2177	hypothetical protein	-
GII78_RS11325	2206454..2206837	-	384	WP_181456319.1	UPF0715 family protein	-
GII78_RS11330	2206936..2207115	-	180	WP_113712869.1	hypothetical protein	-
GII78_RS11335	2207138..2207362	-	225	WP_072692936.1	hypothetical protein	-
GII78_RS11340	2207536..2207901	-	366	WP_113712868.1	hypothetical protein	-
GII78_RS11345	2208230..2209462	-	1233	WP_113712867.1	hypothetical protein	-
GII78_RS11350	2209544..2209732	-	189	WP_113712866.1	hypothetical protein	-
GII78_RS11355	2209777..2209992	-	216	WP_076983670.1	hypothetical protein	-
GII78_RS11360	2210046..2210222	-	177	WP_014470124.1	hypothetical protein	Toxin
-	2210163..2210263	+	101	NuclAT_0	-	Antitoxin
-	2210163..2210263	+	101	NuclAT_0	-	Antitoxin
-	2210163..2210263	+	101	NuclAT_0	-	Antitoxin
-	2210163..2210263	+	101	NuclAT_0	-	Antitoxin
GII78_RS11365	2210709..2211320	-	612	WP_074794693.1	hypothetical protein	-
GII78_RS11370	2211513..2211842	-	330	WP_032721651.1	helix-turn-helix domain-containing protein	-
GII78_RS11375	2212804..2212998	+	195	WP_072692657.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2138055..2271592	133537

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6856.40 Da
• Isoelectric Point: 12.8849

>T142729 WP_014470124.1 NZ_CP045824:c2210222-2210046 [Bacillus subtilis]
VLEKVGIIVAFLISLTVLTINSLTIVEKIRNLKNGTSKKKKRTRKRLRSKRQRKRIRR

Nucleotide

• Length: 177 bp

>T142729 NZ_CP060846:3533301-3533546 [Salmonella enterica]
ATGAATGCCTCCGGCGTCAGCGTCCGCCACATCAACAGCGAAACCTGCATGACCGCCTGTTACTCACAAATCCCCAGCGG
CGACTGCCAGGAAGAAGCGGGATTTGAGACCGGGCGCAGCGTGACGGTGAAGATTTCGGACGGGTGTATTGTGCTAATGG
CGGACGGTAACGAGGTGCAGAAGCTGTGCGAACAGCTTTATCAGGCTGAACAGGTAGTTAAGGGGATGTGGGACGTGATT
GTTTAG

Antitoxin

Nucleotide

• Length: 101 bp

>AT142729 NZ_CP045824:2210163-2210263 [Bacillus subtilis]
GATGGTAAGAACCGTTAAAGATATGAGGAAAGCAACTATGATACCCACTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Structures

Antitoxin