Detailed information of TA system TA142717

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrG-SR6/-
• Location: 2263212..2263501
• Replicon: chromosome
• Accession: NZ_CP045823
• Organism: Bacillus subtilis strain MB8_B1

Toxin (Protein)

• Gene name: bsrG
• Uniprot ID: L8EAY0
• Locus tag: GII79_RS11595
• Protein ID: WP_009967548.1
• Coordinates: 2263212..2263328 (+)
• Length: 39 a.a.

Antitoxin (RNA)

Gene name	SR6
Locus tag	-
Coordinates	2263323..2263501 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GII79_RS11565	2258672..2259910	-	1239	WP_142743355.1	MFS transporter	-
GII79_RS11570	2260023..2261273	-	1251	WP_153912306.1	UV damage repair protein UvrX	-
GII79_RS11575	2261266..2261598	-	333	WP_128473977.1	YolD-like family protein	-
GII79_RS11580	2261772..2262107	+	336	WP_004399073.1	hypothetical protein	-
GII79_RS11585	2262150..2262506	-	357	WP_019712874.1	hypothetical protein	-
GII79_RS11590	2262512..2262979	-	468	WP_128992107.1	DUF4879 domain-containing protein	-
GII79_RS11595	2263212..2263328	+	117	WP_009967548.1	type I toxin-antitoxin system toxin BsrG	Toxin
-	2263323..2263501	-	179	NuclAT_1	-	Antitoxin
-	2263323..2263501	-	179	NuclAT_1	-	Antitoxin
-	2263323..2263501	-	179	NuclAT_1	-	Antitoxin
-	2263323..2263501	-	179	NuclAT_1	-	Antitoxin
GII79_RS11600	2263952..2264428	-	477	WP_080316884.1	SMI1/KNR4 family protein	-
GII79_RS11605	2264529..2265017	-	489	WP_041056186.1	antitoxin YezG family protein	-
GII79_RS11610	2265024..2266934	-	1911	WP_153912308.1	ribonuclease YeeF family protein	-
GII79_RS11615	2267034..2267591	-	558	WP_153912309.1	SMI1/KNR4 family protein	-
GII79_RS11620	2267657..2267910	-	254	Protein_2236	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2136639..2298332	161693

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-38)

Sequences

Toxin

Protein

• Length: 39 a.a.
• Molecular weight: 4336.39 Da
• Isoelectric Point: 10.1022

>T142717 WP_009967548.1 NZ_CP045823:2263212-2263328 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Nucleotide

• Length: 117 bp

>T142717 NZ_CP060844:c1099167-1098856 [Salmonella enterica]
GTGCATGTTATCAGCCGAAAACCGTTCAATGAAGCGATGCTCATGTATCCAAACCATGAGCTTGCCCTCACTGAGTTGCT
GAATGTTCTTGAGAAAAAAACATTCACTCAGCCTGAAGAGATGAAGCGGTATATTCCTTCACTGGATAATTTTAAGTACA
GAGATAAATGGTGGGTGATTGATGTTTCTGATAACAGCCTGAGACTCATTTCCTACATAGATTTCAGGTTACATAAGATA
TTTGTGAAACATATCGTTTCCCATGCCGAATATGACAAACTGACCGCATATTATCGGGGTAATAAAGAATGA

Antitoxin

Nucleotide

• Length: 179 bp

>AT142717 NZ_CP045823:c2263501-2263323 [Bacillus subtilis]
AATGATACAAATAATTATTTTTTGCATTTTGATTTGTAGAAATGCATAAAATAAAAAGACCAGGGTGCTACCAACACCCC
AGCTCTGTACAAAAAGCTGCCCATCAAAGGGCTTGCTCAGATGTATGTGACATAGTAGACCAACCCTTTAGGGTCGCAAT
CTCAAGGGGAGGTCTATTT

Structures

Toxin

• AlphaFold DB: A0A7Z7EVU9

Antitoxin