Detailed information of TA system TA142684

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2048900..2049215
• Replicon: chromosome
• Accession: NZ_CP045821
• Organism: Bacillus subtilis strain MB8_B7

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: GII80_RS10200
• Protein ID: WP_120322743.1
• Coordinates: 2048900..2049061 (+)
• Length: 54 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2049042..2049215 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GII80_RS10185	2044128..2044463	+	336	WP_009967409.1	hypothetical protein	-
GII80_RS10190	2044510..2048115	-	3606	WP_004399367.1	membrane protein	-
GII80_RS10195	2048348..2048680	-	333	WP_026009814.1	hypothetical protein	-
GII80_RS10200	2048900..2049061	+	162	WP_120322743.1	putative holin-like toxin	Toxin
-	2049042..2049215	-	174	-	-	Antitoxin
GII80_RS10205	2049330..2050172	-	843	WP_003231327.1	hypothetical protein	-
GII80_RS10210	2050372..2050830	-	459	WP_003231326.1	type II toxin-antitoxin system antitoxin YobK	-
GII80_RS10215	2050840..2052641	-	1802	Protein_1957	type II toxin-antitoxin system toxin ribonuclease YobL	-
GII80_RS10220	2052743..2053300	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2025015..2060179	35164

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (24-47)

Sequences

Toxin

Protein

• Length: 54 a.a.
• Molecular weight: 5780.74 Da
• Isoelectric Point: 4.6641

>T142684 WP_120322743.1 NZ_CP045821:2048900-2049061 [Bacillus subtilis]
ISCTVSFAHSRESCSSPNERGDAMSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 162 bp

>T142684 NZ_CP060834:317650-318003 [Salmonella enterica]
ATCTCAGCGGAAGAGATAATTCAGTTTCACGACAGGCTTCTCCGCGTTACGCCTGGTGTAACAGGCATGCCTGATCCTGG
GCGCGCGGAAGCGCTAATGTACCGGGTACTCAATCAAATCGAATATGAAGGGGTGACCGACGTGTGGCTGCTGGCGGCAA
TGCATTTGCTCGCTATATCCCGTGGGCATATCTTCAATGATGGTAACAAACGTACCGCCTTATTTATTACGCTGCTGTTT
TTAAAGCGTAACGGGATCTCACTCGCTGCGAATCCGGATTTTGTCGATATGACAGTCGATGCGGCGGCAGGGCGGCTTAC
GCTGGAGCAAATTGTCGTTCGCTTACGCGCCTGA

Antitoxin

Nucleotide

• Length: 174 bp

>AT142684 NZ_CP045821:c2049215-2049042 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin