Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) bsrE-as-bsrE/-
Location 2069405..2069720 Replicon chromosome
Accession NZ_CP045812
Organism Bacillus subtilis strain P8_B3

Toxin (Protein)


Gene name bsrE Uniprot ID -
Locus tag GII89_RS10325 Protein ID WP_120322743.1
Coordinates 2069405..2069566 (+) Length 54 a.a.

Antitoxin (RNA)


Gene name as-bsrE
Locus tag -
Coordinates 2069547..2069720 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GII89_RS10310 2064633..2064968 + 336 WP_009967409.1 hypothetical protein -
GII89_RS10315 2065015..2068620 - 3606 WP_004399367.1 membrane protein -
GII89_RS10320 2068853..2069185 - 333 WP_026009814.1 hypothetical protein -
GII89_RS10325 2069405..2069566 + 162 WP_120322743.1 putative holin-like toxin Toxin
- 2069547..2069720 - 174 - - Antitoxin
GII89_RS10330 2069835..2070677 - 843 WP_003231327.1 hypothetical protein -
GII89_RS10335 2070877..2071335 - 459 WP_003231326.1 type II toxin-antitoxin system antitoxin YobK -
GII89_RS10340 2071345..2073147 - 1803 WP_004399481.1 type II toxin-antitoxin system toxin ribonuclease YobL -
GII89_RS10345 2073249..2073806 - 558 WP_004399321.1 SMI1/KNR4 family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2055459..2081338 25879


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(24-47)


Sequences


Toxin        


Download         Length: 54 a.a.        Molecular weight: 5780.74 Da        Isoelectric Point: 4.6641

>T142631 WP_120322743.1 NZ_CP045812:2069405-2069566 [Bacillus subtilis]
ISCTVSFAHSRESCSSPNERGDAMSTFQALMLMLAIGSFIIALLTYIEKIDLP

Download         Length: 162 bp

>T142631 NZ_CP060796:c2509937-2509836 [Enterococcus faecalis]
TTGTCAATCGAAGCGGCATTGGAATTGATGATTAGTTTTGCAACCCTTGTTGCGTTACTGATTTTCGGTATCCTTGAAGC
AACGAAAAACAATAAAAAATAA

Antitoxin


Download         Length: 174 bp

>AT142631 NZ_CP045812:c2069720-2069547 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References