Detailed information of TA system TA142626

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2048842..2049157
• Replicon: chromosome
• Accession: NZ_CP045811
• Organism: Bacillus subtilis strain P9_B1

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: GII90_RS10200
• Protein ID: WP_120322743.1
• Coordinates: 2048842..2049003 (+)
• Length: 54 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2048984..2049157 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GII90_RS10185	2044070..2044405	+	336	WP_009967409.1	hypothetical protein	-
GII90_RS10190	2044452..2048057	-	3606	WP_004399367.1	membrane protein	-
GII90_RS10195	2048290..2048622	-	333	WP_026009814.1	hypothetical protein	-
GII90_RS10200	2048842..2049003	+	162	WP_120322743.1	putative holin-like toxin	Toxin
-	2048984..2049157	-	174	-	-	Antitoxin
GII90_RS10205	2049272..2050114	-	843	WP_003231327.1	hypothetical protein	-
GII90_RS10210	2050314..2050772	-	459	WP_003231326.1	type II toxin-antitoxin system antitoxin YobK	-
GII90_RS10215	2050782..2052584	-	1803	WP_004399481.1	type II toxin-antitoxin system toxin ribonuclease YobL	-
GII90_RS10220	2052686..2053243	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2034896..2060122	25226

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (24-47)

Sequences

Toxin

Protein

• Length: 54 a.a.
• Molecular weight: 5780.74 Da
• Isoelectric Point: 4.6641

>T142626 WP_120322743.1 NZ_CP045811:2048842-2049003 [Bacillus subtilis]
ISCTVSFAHSRESCSSPNERGDAMSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 162 bp

>T142626 NZ_CP060794:c2397429-2397220 [Staphylococcus epidermidis]
ATGAAATTGAAAAAAGGATTGATAAATGTTTCAGGTATTAAAACAACTGAACAAGCTAAACAGCTCAAAGATCATTTATC
TAAGATGATAGGCATCAATAGTGTGGATATCGATTACCAAATGAATGAGATTCGAGTAGAATTTGACACTCCTGCAAATT
TAAATAACATTGAAAAAGAAATTTACGATTACGGATTTCGTATTTTGTAA

Antitoxin

Nucleotide

• Length: 174 bp

>AT142626 NZ_CP045811:c2049157-2048984 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin