142495

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 4379376..4379881 Replicon chromosome
Accession NZ_CP045767
Organism Pseudomonas sp. CFSAN084952

Toxin (Protein)


Gene name yoeB Uniprot ID A0A0W0MVT7
Locus tag GH769_RS19905 Protein ID WP_014719853.1
Coordinates 4379627..4379881 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID I4K3F7
Locus tag GH769_RS19900 Protein ID WP_003194039.1
Coordinates 4379376..4379630 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GH769_RS19885 4374817..4376718 + 1902 WP_032903661.1 alkaline phosphatase family protein -
GH769_RS19890 4376857..4377870 + 1014 WP_019817488.1 sensor domain-containing diguanylate cyclase -
GH769_RS19895 4377981..4379231 + 1251 WP_153649878.1 aspartate aminotransferase family protein -
GH769_RS19900 4379376..4379630 + 255 WP_003194039.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
GH769_RS19905 4379627..4379881 + 255 WP_014719853.1 Txe/YoeB family addiction module toxin Toxin
GH769_RS19910 4379980..4380696 + 717 WP_032903659.1 hypothetical protein -
GH769_RS19915 4380707..4381828 - 1122 WP_014719855.1 aminotransferase class V-fold PLP-dependent enzyme -
GH769_RS19920 4381830..4383032 - 1203 WP_019817486.1 MFS transporter -
GH769_RS19925 4383032..4384282 - 1251 WP_014719857.1 ATP-grasp domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9977.51 Da        Isoelectric Point: 8.0456

>T142495 WP_014719853.1 NZ_CP045767:4379627-4379881 [Pseudomonas sp. CFSAN084952]
MKILFTPEGWDDYLWFQQNDKAGLKRINLLIKAIQRDPFGGVGKPEPLKHNLSGFWSRRITAEHRLVYGIEDDEVQILMC
RYHY

Download         Length: 255 bp

>T142495 NZ_CP060708:4397690-4397863 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9576.93 Da        Isoelectric Point: 7.2034

>AT142495 WP_003194039.1 NZ_CP045767:4379376-4379630 [Pseudomonas sp. CFSAN084952]
METINYTNARAHLSETMDRVNDDHVPLLLTRQKGEPVVMISLSEFNALEETAYLLRSPKNAERLINSVNSLRAGKAKPRR
LIEE

Download         Length: 255 bp

>AT142495 NZ_CP060708:4397366-4397662 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGATT
AAGATCATTGATGTATGATATGAATTTCTCCTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAACT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTCAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0W0MVT7

Antitoxin

Source ID Structure
AlphaFold DB A0A0W0MVN5

References