Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 204170..204683 Replicon chromosome
Accession NZ_CP045729
Organism Limosilactobacillus gastricus strain LG045

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag LG045_RS00920 Protein ID WP_056937554.1
Coordinates 204170..204424 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LG045_RS00925 Protein ID WP_056937555.1
Coordinates 204417..204683 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LG045_RS00900 199756..200646 + 891 WP_056937550.1 LysR family transcriptional regulator -
LG045_RS00905 201027..201767 + 741 WP_056937551.1 cyclase family protein -
LG045_RS00910 201802..202913 + 1112 Protein_176 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase -
LG045_RS00915 202930..204039 + 1110 WP_056937553.1 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase -
LG045_RS00920 204170..204424 - 255 WP_056937554.1 Txe/YoeB family addiction module toxin Toxin
LG045_RS00925 204417..204683 - 267 WP_056937555.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LG045_RS00930 204891..205550 - 660 WP_056937556.1 thiaminase II -
LG045_RS00935 205552..206067 - 516 WP_056937557.1 energy coupling factor transporter S component ThiW -
LG045_RS00940 206376..207233 + 858 WP_056937558.1 alpha/beta hydrolase -
LG045_RS00945 207278..207709 - 432 WP_007122049.1 Hsp20/alpha crystallin family protein -
LG045_RS00950 207905..208666 + 762 WP_056937559.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10557.11 Da        Isoelectric Point: 9.9084

>T142415 WP_056937554.1 NZ_CP045729:c204424-204170 [Limosilactobacillus gastricus]
MFNFTEQAWKDYIPWQREDKKILKRINRLIDDIKRNPFEGIGKPEPLKYRYSGTWSRRINDEHRLVYMVEKDEIFFLSFR
DHYK

Download         Length: 255 bp

>T142415 NZ_CP060677:44889-46214 [Salmonella enterica]
ATGAGCCGGAAACAGCAACGTCTGGTAATTTGGATGAACGGCATCAAAGTCGGGTACTGGGAAAAAAGCAAAGGGGTAGA
CAGCTTAGAATACCTTCCTGAATGGGTTGCTGACGAACAGGGAAGGCCGCTGTCATTGTCCCTTCCTTTTACTCCCGGGA
ACCAGGTCTGGCGTGGAAATGTGGTACGTGACTATTTTGATAATTTACTGCCGGACAGCGAAGGCATACGCAGACGTCTG
GCAATGCGTTACAAGGCCGATAGCCTGGAGCCTTTTGATCTGCTGACGGAGCTGGGAAAAGACTGCGTGGGCGCGATACA
GCTGCTTCATGACGGAGATGAACCCACTGATTTATATTCCGTGAAGTATCACCCGCTTACTGAATCAGAAATTGCGGCAA
CTTTGCGTAATACCACGGAGACATTGCTACCGGGCAGGCCAGAAGATAACGACGACTTACGTTTATCTATTGCCGGTGCT
CAGGAGAAAACAGCCCTACTGTGGCATGAAGATCGGTGGTGTATGCCGGAGGGTAATACACCAACGACGCATATATTCAA
GCTACCGCTCGGACTTGTGGGGAACATGAAAGCCGACATGAGCTCGTCGGTTGAAAATGAATGGCTCTGCTCGGTACTTC
TCGGCCAGTACGGGCTCCCCGTGGCAAGAACGCAGATTGCTCACTTTGAAGATCAGAAAGCGCTGGTGGTAGAACGTTTT
GACCGAAAATGGTCAGGAGACGGACAATGGATCATTCGTTTACCCCAGGAGGATATGTGTCAGGCCCTGGGCGTTTCGCC
ATTACGAAAATATCAGGCGGACGGCGGGCCAGGTATATCGGAAATTATGGAGGTTCTGAGTAATTCAGACCGTGCTGAGC
GTGACAAAGCGCAGTTTTTTATGACGCAGATAATTTTCTGGATGATGGCCGCAACAGATGGCCACGCTAAAAATTTCAGT
ATTTCTATTGGGCCACAGGGACGTTATCACCTTACACCAAACTATGATGTGTTGTCGGCATGGCCGGTGATCGGTCATGG
GAACAATCAGATATCCTGGCAGAAGTGCAAACTGGCGATGGCCGTACGTGGCAGTAGCAACTATTACCAGATATATCGAA
TACAACGACGCCACTGGATCAGGCATGGTGAGATAACCGGCCTGAGTAAACAGCAGACAGAGGCGATGATAGAGGAAATC
ATCGCCAGAACCCCGGGTGTCATTGAACGTGTTAGCGGGCTTCTTCCGGACCAGTTCCCCCAGCAGCTTGCGGAAAGTAT
TTTTGATGGAATGAGGCAGCAATGCAGGCGCCTGGCTGAGAAATGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10420.65 Da        Isoelectric Point: 4.1653

>AT142415 WP_056937555.1 NZ_CP045729:c204683-204417 [Limosilactobacillus gastricus]
MDAIVYSNFRNNLKDYMKKVNDEYEPLMVVNKNPDEDIVVLSKENWDSIQETIRLMSNEYLSDKVLSGIEQVKQRNVEQH
QLVEDEDV

Download         Length: 267 bp

>AT142415 NZ_CP060677:44591-44884 [Salmonella enterica]
ATCAATAATGATTACCCGTTAAACACGCTCAACCAGCTGCGTCCCTTGCTCATTGGTTTTCGCAAGGCGAATGGCCTGAC
GCAAAAAGACCTGTCCGAAAGGTTAGGCGTCACTCAACAGACATACTCACGTCTGGAAGCCAACCCTGCCAGTGCGAGCA
TTGAACGGCTATTCAAGGTGTTTTCCATCCTGGGCGTAAAAATCAGCTTCTCCTCGGCAACCACCTCTTCAGAGAGGAAG
CAGACGGAAGAAATGCTTAAATCAAACTCACCTGCACGACAGGAGGATTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References