142394

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 356372..356987 Replicon chromosome
Accession NZ_CP045725
Organism Raineyella sp. CBA3103

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag Rai3103_RS01630 Protein ID WP_153571124.1
Coordinates 356631..356987 (+) Length 119 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag Rai3103_RS01625 Protein ID WP_153571123.1
Coordinates 356372..356629 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Rai3103_RS01605 351948..352568 - 621 WP_153571120.1 M23 family metallopeptidase -
Rai3103_RS01610 352682..353542 - 861 WP_153571121.1 aldo/keto reductase -
Rai3103_RS01615 353552..354790 - 1239 WP_153571122.1 Fic family protein -
Rai3103_RS01620 355093..356316 + 1224 WP_153573554.1 hypothetical protein -
Rai3103_RS01625 356372..356629 + 258 WP_153571123.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
Rai3103_RS01630 356631..356987 + 357 WP_153571124.1 Txe/YoeB family addiction module toxin Toxin
Rai3103_RS01635 356948..357571 + 624 WP_153571125.1 GntR family transcriptional regulator -
Rai3103_RS01640 357717..358554 + 838 Protein_322 fumarylacetoacetate hydrolase family protein -
Rai3103_RS01645 358551..359309 + 759 WP_153571126.1 alpha/beta fold hydrolase -
Rai3103_RS01650 359428..360707 + 1280 Protein_324 amidohydrolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 119 a.a.        Molecular weight: 13900.62 Da        Isoelectric Point: 10.4878

>T142394 WP_153571124.1 NZ_CP045725:356631-356987 [Raineyella sp. CBA3103]
VLLVWDENAWEDYLWWQAQDRRVLKRINTLLADIQRNGNEGIGKPEALKHDVADYWSRRITDEHRLVYKAAGNEVRVPAC
RYHQHAYTTPSRITRGRRSSSGRLRRWTTPTSPSACRQ

Download         Length: 357 bp

>T142394 NZ_CP060674:c4451861-4451550 [Salmonella enterica]
GTGCATGTTATCAGCCGAAAACCGTTCAATGAAGCGATGCTCATGTATCCAAACCATGAGCTTGCTCTCACTGAGTTGCT
GAATGTTCTGGAGAAAAAAACACTCACTCAGCCTGAAGAGATGAAGCGGTATATTCCTTCACTGGATAATTTTAAGCACA
GAGATAAATGGTGGGTGATTGATGTTTCTGGTAACAGCCTGAGACTCATTTCCTACATAGATTTCAGGTTACATAAGATA
TTTGTGAAACATATCGTTTCCCATGCCGAATATGACAAACTGACCGCATATGATCGGGGTAATAAAGAATGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9625.72 Da        Isoelectric Point: 4.4280

>AT142394 WP_153571123.1 NZ_CP045725:356372-356629 [Raineyella sp. CBA3103]
MKTMSYTESRARYAEVLDAVVNDREEVVITRAGHEPVVIVSLEDYESLRETAYLMRSPANARRLLDAMERLESGGGQQHD
PVETD

Download         Length: 258 bp

>AT142394 NZ_CP060674:c4451553-4451107 [Salmonella enterica]
ATGAGAACTCATCGTCAGATGGATGCAACCAGCGCAAAAAAGATCGTTGATACCTTCAGCGATGCGGTAAAAAGCGTCCC
ACTGATGGGGGAAGACCGAAATGACAATGAGTATCGCAGGGCACTAGCGCTAGTGGAGTTTCTGGTCGACCACGACGATC
TTGAAAACCCACTATTTGAATTGCTCTGTGCCCGAATCAGTGAATACGAAAAACATGCGCCGGAATTCAAAGCACTCAAC
CAACACCTGGAGAAAACGCCCCCTGGCGTTTCAGTATTGCGAACGCTCATGGATCAATACGGTCTCAAAGCAGCAGATCT
TGCCAACGAACTTGGTTCTAAATCGAACGTCAGCAACATCTTAAATGGCCGCAGAGCACTAACGGTTAATCATATTAAAG
CGCTTACACAACGCTTCAAACTACCAGCAGATGCCTTCATCGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References