Detailed information of TA system TA142391

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): prlF-yhaV (relBE)/YhaV-PrlF
• Location: 368064..368885
• Replicon: plasmid pEuc1
• Accession: NZ_CP045721
• Organism: Pantoea eucalypti strain LMG 24197

Toxin (Protein)

• Gene name: yhaV
• Uniprot ID: -
• Locus tag: EE896_RS20610
• Protein ID: WP_140915932.1
• Coordinates: 368415..368885 (+)
• Length: 157 a.a.

Antitoxin (Protein)

• Gene name: prlF
• Uniprot ID: -
• Locus tag: EE896_RS20605
• Protein ID: WP_140915933.1
• Coordinates: 368064..368408 (+)
• Length: 115 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EE896_RS20590	364067..365176	+	1110	WP_003851511.1	maltose/maltodextrin ABC transporter ATP-binding protein MalK	-
EE896_RS20595	365220..366521	+	1302	WP_105099698.1	maltoporin	-
EE896_RS20600	366626..367564	+	939	WP_140915934.1	maltose operon protein MalM	-
EE896_RS20605	368064..368408	+	345	WP_140915933.1	type II toxin-antitoxin system PrlF family antitoxin	Antitoxin
EE896_RS20610	368415..368885	+	471	WP_140915932.1	type II toxin-antitoxin system YhaV family toxin	Toxin
EE896_RS20615	369073..371148	-	2076	WP_140915931.1	4-alpha-glucanotransferase	-
EE896_RS20620	371157..373559	-	2403	WP_140915930.1	maltodextrin phosphorylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	pla	1..529303	529303

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin endonuclease, YhaV (12-148)

Antitoxin

• PrlF antitoxin (15-113)

Sequences

Toxin

Protein

• Length: 157 a.a.
• Molecular weight: 18275.71 Da
• Isoelectric Point: 8.4645

>T142391 WP_140915932.1 NZ_CP045721:368415-368885 [Pantoea eucalypti]
MEDGTVINGWHVYVHPCFESQLIALTNEVESLRAKYPESYQRKATTKLLAAVFKVINSEICADPHHAKFRQGDTLGEQNK
HWFRAKFLMQYRLFFRFSEQHKTIILAWMNDAETKRAYGSKRDAYKVFSGMLHNGYPPDDWALLLKQSQDWDNTNS

Nucleotide

• Length: 471 bp

>T142391 NZ_CP060674:c3903427-3903152 [Salmonella enterica]
ATGGGGCAAAGGGAAATTGAATATTCGGGACAGTTCCAGAAAGATGTAAAACGGGCACAAAAGCGTCATAAGGATGTCGG
CAAACTTAAAACACTTATGACGCTTCTGATTCACCACCCTTTTCCCCTTCCTGCCATTTATAAAGATCACCCGTTACAAG
GTTCATATAGCGGATACCGGGATGCCCATATTGAGCCTGACTGGATTCTTATTTATAAGATAACGGATGAATGCCTGCGA
TTTGAACGAACAGGAACGCATGCCGATTTATTTTAA

Antitoxin

Protein

• Length: 115 a.a.
• Molecular weight: 12295.00 Da
• Isoelectric Point: 4.2091

>AT142391 WP_140915933.1 NZ_CP045721:368064-368408 [Pantoea eucalypti]
MGTLTHTNISLRATSKLTARSQTTIPAAVRDAMNLQPGENIEYAVLPGGKVLITRQETVTDDDPVMASFLSFLAADMCNT
PANIKTLDRGLLTRITSLTEGMDVDLDAPLMDDE

Nucleotide

• Length: 345 bp

>AT142391 NZ_CP060674:c3903690-3903430 [Salmonella enterica]
ATGGCTGCAAATGCGCTTGTTCGTGCCCGTATCGACGAAACGCTGAAGGACCAGGCGGCAGATGTCCTGGCTGAAATGGG
GTTAACCATTTCTGATTTGATACGGATTACACTGACTAAAGTTGCGCGTGAAAAGGCATTGCCTTTTGATTTGCGCATAC
CCAATGAGTTAACGTCACGAACGATAGAAAATAGCGAAGCTGGCGTTGATATTCATAAAGCCAAAGATGCTGATGATTTG
TTTGACCAGTTAGGGATCTGA