Detailed information of TA system TA142387

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): symER/SymE(toxin)
• Location: 3553916..3554316
• Replicon: chromosome
• Accession: NZ_CP045720
• Organism: Pantoea eucalypti strain LMG 24197

Toxin (Protein)

• Gene name: symE
• Uniprot ID: -
• Locus tag: EE896_RS16625
• Protein ID: WP_078804792.1
• Coordinates: 3553916..3554245 (-)
• Length: 110 a.a.

Antitoxin (RNA)

Gene name	symR
Locus tag	-
Coordinates	3554263..3554316 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EE896_RS16595	3549634..3550218	-	585	WP_140916162.1	DJ-1/PfpI family protein	-
EE896_RS16600	3550509..3551318	-	810	WP_140916193.1	CDP-diacylglycerol diphosphatase	-
EE896_RS16605	3551388..3551696	-	309	WP_003850923.1	hypothetical protein	-
EE896_RS16610	3551715..3552140	-	426	WP_039658869.1	hypothetical protein	-
EE896_RS16615	3552137..3552838	-	702	WP_039658871.1	hypothetical protein	-
EE896_RS16620	3552993..3553349	-	357	WP_110411681.1	hypothetical protein	-
EE896_RS16625	3553916..3554245	-	330	WP_078804792.1	endoribonuclease SymE	Toxin
-	3554263..3554316	+	54	NuclAT_0	-	Antitoxin
-	3554263..3554316	+	54	NuclAT_0	-	Antitoxin
-	3554263..3554316	+	54	NuclAT_0	-	Antitoxin
-	3554263..3554316	+	54	NuclAT_0	-	Antitoxin
-	3554263..3554316	+	54	NuclAT_1	-	Antitoxin
-	3554263..3554316	+	54	NuclAT_1	-	Antitoxin
-	3554263..3554316	+	54	NuclAT_1	-	Antitoxin
-	3554263..3554316	+	54	NuclAT_1	-	Antitoxin
EE896_RS16630	3554505..3554635	-	131	Protein_3244	restriction endonuclease subunit S	-
EE896_RS16635	3555025..3555798	+	774	WP_110411682.1	type IV toxin-antitoxin system AbiEi family antitoxin	-
EE896_RS16640	3555791..3555979	+	189	Protein_3246	nucleotidyl transferase AbiEii/AbiGii toxin family protein	-
EE896_RS16645	3556345..3557358	-	1014	WP_140916161.1	restriction endonuclease	-
EE896_RS16650	3557473..3558069	-	597	WP_140916160.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3551715..3566774	15059

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (20-71)

Sequences

Toxin

Protein

• Length: 110 a.a.
• Molecular weight: 12067.89 Da
• Isoelectric Point: 9.1097

>T142387 WP_078804792.1 NZ_CP045720:c3554245-3553916 [Pantoea eucalypti]
MTDAHSIAQLSEPEVSPSNNRQLTVGYASRYPDYSRIPAITMKGQWLEAAGFVTGTAVEVKVMEGCIVLTARQESELVQS
LRQVCKLSARKQKQVQEFIQVISGKQKVV

Nucleotide

• Length: 330 bp

>T142387 NZ_CP060674:1817475-1817630 [Salmonella enterica]
ATGAAGCAGCAAAAGGCGATGTTAATCGCCCTGATCGTCATCTGTTTAACCGTCATAGTGACGGCACTGGTAACGAGGAA
AGACCTCTGCGAGGTACGAATCCGAACCGGCCAGACGGAGGTCGCTGTCTTCACAGCTTACGAACCTGAGGAGTAA

Antitoxin

Nucleotide

• Length: 54 bp

>AT142387 NZ_CP045720:3554263-3554316 [Pantoea eucalypti]
AATAGTGATTGTGATTAGCGGCGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Structures

Antitoxin