142112

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1937654..1938354 Replicon chromosome
Accession NZ_CP045551
Organism Pseudomonas putida strain 15420352

Toxin (Protein)


Gene name mqsR Uniprot ID A0A2I0CDW7
Locus tag GEV41_RS08910 Protein ID WP_003254238.1
Coordinates 1937654..1937950 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID I7AUJ7
Locus tag GEV41_RS08915 Protein ID WP_003254235.1
Coordinates 1937953..1938354 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GEV41_RS08890 1933290..1934915 + 1626 WP_102885731.1 PvdJ/PvdD/PvdP-like protein -
GEV41_RS08895 1935037..1935513 + 477 WP_003254241.1 sigma-70 family RNA polymerase sigma factor -
GEV41_RS08900 1935682..1936161 + 480 WP_003254240.1 hypothetical protein -
GEV41_RS08905 1936234..1937559 + 1326 WP_047604115.1 MFS transporter -
GEV41_RS08910 1937654..1937950 + 297 WP_003254238.1 type II toxin-antitoxin system MqsR family toxin Toxin
GEV41_RS08915 1937953..1938354 + 402 WP_003254235.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
GEV41_RS08920 1938426..1940108 - 1683 WP_010954959.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
GEV41_RS08925 1940644..1941393 + 750 WP_003254232.1 electron transfer flavoprotein subunit beta/FixA family protein -
GEV41_RS08930 1941395..1942336 + 942 WP_047604111.1 FAD-binding protein -
GEV41_RS08935 1942412..1943233 + 822 WP_003254229.1 transporter substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(6-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-109)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11110.18 Da        Isoelectric Point: 10.2270

>T142112 WP_003254238.1 NZ_CP045551:1937654-1937950 [Pseudomonas putida]
MEKRMPNCPLERVKALAAARRIRPTGAALKGAKALGMDFPGMLEVITSLKRTDFYKSMTSHIDHRVWQDVYRPLTAIGYV
YLKLSVVDDVLIVSFKEL

Download         Length: 297 bp

>T142112 NZ_CP060398:c3238306-3237908 [Synechococcus sp. CBW1002]
ATGTTGCGCTATCTGCTGGATACCAATATCTGCATCTATGTGATCAAGCAAAGGCCGGCTTCGCTGCTTGAGAGATTCAA
CGAGAATGCTGCCCTGATGGGGATCTCTGCGATCACCCTGGCCGAGTTGCTGCACGGGGCTGAAAAGAGTTCCCAACCCC
GGAGATCTCTTGCCGTTGTGGAGGACTTCTGCAGTCGCTTGGATGTGCTCAGCTACGGAGCCAAAGCTGCGCAGCACTAT
GGACTGATTCGCGCATCCCTTGAGCGGCGTGGATTACCGATTGGTGTGAATGATCTGCACATCGCTGCCCATGCCCGCAG
TGAGGGCCTGACCCTGGTCAGCAACAACCTGCGGGAATTCGAGCGGGTGGATGGTCTGTTGCTCGACAACTGGGTCTGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14684.76 Da        Isoelectric Point: 4.9531

>AT142112 WP_003254235.1 NZ_CP045551:1937953-1938354 [Pseudomonas putida]
MRCPICGGSELAPDIQGMPYSYKGEMTVIPEVSGDYCSACGECVLSHDEAMRVSHLMTAFERQVNANVVDPSFIASIRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA

Download         Length: 402 bp

>AT142112 NZ_CP060398:c3238551-3238315 [Synechococcus sp. CBW1002]
GTGGCGGCTGTCACCAGGCTCTTCCTCAGTAACCGCAGTCAGGCTGTGCGCATCCCCGCCCATCTGCGCCTGCCTGACTC
CGTGAAAGACGTGGAGGTCCGGGCCTGCGGCGAGGAGCGCATCATCTCTCCGCTCGGTCGCCGCTGGGACACGTTCTTTC
AGGATGCGCTGCCCGTGCCGGATGACTTCCTGCAGGAGAGGGCGACTCAGGATCAACCGGAGCGCGAGGCCTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I0CDW7

Antitoxin

Source ID Structure
AlphaFold DB I7AUJ7

References