Detailed information of TA system TA141909

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 1920835..1921019
• Replicon: chromosome
• Accession: NZ_CP045472
• Organism: Staphylococcus aureus strain ZY05

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: A0A2P7CQJ7
• Locus tag: GAY69_RS09125
• Protein ID: WP_000482647.1
• Coordinates: 1920835..1920942 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	1920959..1921019 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GAY69_RS09100	1916197..1916670	+	474	WP_000456483.1	GyrI-like domain-containing protein	-
GAY69_RS09105	1916793..1918004	-	1212	WP_001191921.1	multidrug effflux MFS transporter	-
GAY69_RS09110	1918187..1918846	-	660	WP_000831298.1	membrane protein	-
GAY69_RS09115	1918906..1920048	-	1143	WP_001176863.1	glycerate kinase	-
GAY69_RS09120	1920316..1920702	+	387	WP_000779353.1	flippase GtxA	-
GAY69_RS09125	1920835..1920942	+	108	WP_000482647.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	1920959..1921019	-	61	-	-	Antitoxin
GAY69_RS09130	1920969..1921136	+	168	WP_000301893.1	hypothetical protein	-
GAY69_RS09135	1921590..1923302	+	1713	WP_001064821.1	ABC transporter ATP-binding protein/permease	-
GAY69_RS09140	1923378..1925111	+	1734	WP_000488493.1	ABC transporter ATP-binding protein/permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	1925458..1927104	1646

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4012.76 Da
• Isoelectric Point: 10.4935

>T141909 WP_000482647.1 NZ_CP045472:1920835-1920942 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T141909 NZ_CP060193:c3623179-3622829 [Bacillus sp. PAMC26543]
TTGATTGTGAAACGCGGCGATGTTTATTTTGCTGATTTATCTCCTGTTGTTGGCTCAGAGCAAGGCGGGGTGCGCCCGGT
TTTAGTGATCCAAAATGACATCGGAAATCGCTTCAGCCCAACTGCTATTGTTGCAGCCATAACAGCCCAAATACAGAAAG
CGAAATTACCAACCCACGTCGAAATTGATGCAAAACGCTACGGTTTTGAAAGAGATTCCGTTATTTTGCTGGAGCAAATT
CGGACGATTGACAAGCAAAGGTTAACGGATAAGATTACTCATCTGGATGATGAAATGATGGATAAGGTTGATGAAGCCTT
ACAGATCAGTTTGGCACTCATTGATTTTTAG

Antitoxin

Nucleotide

• Length: 61 bp

>AT141909 NZ_CP045472:c1921019-1920959 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Toxin

• AlphaFold DB: A0A2P7CQJ7

Antitoxin