Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2587894..2588078 Replicon chromosome
Accession NZ_CP045435
Organism Staphylococcus aureus strain 08-028

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag SA08028_RS13175 Protein ID WP_000482647.1
Coordinates 2587971..2588078 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2587894..2587954 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SA08028_RS13160 2583368..2583535 - 168 WP_001790576.1 hypothetical protein -
SA08028_RS13165 2583766..2585499 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
SA08028_RS13170 2585524..2587287 - 1764 WP_001064816.1 ABC transporter ATP-binding protein/permease -
- 2587894..2587954 + 61 - - Antitoxin
SA08028_RS13175 2587971..2588078 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
SA08028_RS13180 2588212..2588598 - 387 WP_000779360.1 flippase GtxA -
SA08028_RS13185 2588856..2589998 + 1143 WP_001176871.1 glycerate kinase -
SA08028_RS13190 2590058..2590717 + 660 WP_000831301.1 membrane protein -
SA08028_RS13195 2590899..2592110 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
SA08028_RS13200 2592233..2592706 - 474 WP_000456497.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T141809 WP_000482647.1 NZ_CP045435:c2588078-2587971 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T141809 NZ_CP060115:c330990-330733 [Fusobacterium hwasookii]
ATGTTATTAACTTGGACCGATTTTGCATCGAAACAATATGAAGAGCTACAAGAGAAGGATAAAAGGCTTATAAAGAAGAT
AAATATACTTATTAAGGATATAAAAAGAAATGGAAATGAAGGAATAGGTAAACCAGAGCCTTTACAACATGAGTTAAGTG
GCTATTGGAGTAGAAGAATTGATGATAAAAATAGATTAGTCTATAAAGTATCAGATAATCAAATAACAATAGTTGCTTGT
GCAAATCATTATAAGTAA

Antitoxin


Download         Length: 61 bp

>AT141809 NZ_CP045435:2587894-2587954 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References