Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2309652..2309868 Replicon chromosome
Accession NZ_CP045435
Organism Staphylococcus aureus strain 08-028

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SA08028_RS11735 Protein ID WP_001802298.1
Coordinates 2309764..2309868 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2309652..2309707 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SA08028_RS11715 2305855..2306520 - 666 WP_001024095.1 SDR family oxidoreductase -
SA08028_RS11720 2306672..2306992 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SA08028_RS11725 2306994..2307974 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
SA08028_RS11730 2308240..2309331 + 1092 WP_000495683.1 hypothetical protein -
- 2309652..2309707 + 56 - - Antitoxin
SA08028_RS11735 2309764..2309868 - 105 WP_001802298.1 hypothetical protein Toxin
SA08028_RS11740 2310548..2310706 + 159 WP_001792784.1 hypothetical protein -
SA08028_RS11745 2311364..2312223 - 860 Protein_2280 Cof-type HAD-IIB family hydrolase -
SA08028_RS11750 2312291..2313073 - 783 WP_000908178.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T141806 WP_001802298.1 NZ_CP045435:c2309868-2309764 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T141806 NZ_CP060111:c4886476-4886219 [Klebsiella michiganensis]
ATGAATCTATCCCGTCAGGAACAACGTACCTTACACGTTCTCGCTAAAGGTGGCCGGATCGCGCACATCCGCGATGCATC
AGGCCGCGTCACCTCTGTTGAATGCTACAGCCGCGAAGGGCTCCTGCTCAGCGACTGCACGCTCGCCGTTTTCAAAAAAC
TCAAAACCAAAAAGCTGATTAAGTCCGTCAACGGACAGCCCTACCGCATCAATACCACCGGGCTGAATAACGTCCGCGCA
CAGCTGGACAATCGCTAA

Antitoxin


Download         Length: 56 bp

>AT141806 NZ_CP045435:2309652-2309707 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References