Detailed information of TA system TA141797

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1975074..1975256
• Replicon: chromosome
• Accession: NZ_CP045435
• Organism: Staphylococcus aureus strain 08-028

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: SA08028_RS09770
• Protein ID: WP_001801861.1
• Coordinates: 1975074..1975169 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1975197..1975256 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SA08028_RS09735	1970744..1971370	+	627	WP_000669017.1	hypothetical protein	-
SA08028_RS09740	1971411..1971752	+	342	WP_000627541.1	DUF3969 family protein	-
SA08028_RS09745	1971853..1972425	+	573	WP_000414202.1	hypothetical protein	-
SA08028_RS09750	1972623..1973180	-	558	Protein_1924	ImmA/IrrE family metallo-endopeptidase	-
SA08028_RS09755	1973554..1973730	-	177	WP_000375477.1	hypothetical protein	-
SA08028_RS09760	1973741..1974124	-	384	WP_000070811.1	hypothetical protein	-
SA08028_RS09765	1974728..1974871	-	144	WP_001549059.1	transposase	-
SA08028_RS09770	1975074..1975169	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1975197..1975256	-	60	-	-	Antitoxin
SA08028_RS09775	1975292..1975393	+	102	WP_001791893.1	hypothetical protein	-
SA08028_RS09780	1975371..1975547	-	177	Protein_1930	transposase	-
SA08028_RS09785	1975741..1976118	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T141797 WP_001801861.1 NZ_CP045435:1975074-1975169 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T141797 NZ_CP060096:576034-576294 [Aceticella autotrophica]
ATGAATAAAATGTTTACGGATATTGCATGGGAAGATTATGAATATTGGCAGATTAATGATAGGAAAATACTCAAAAAGAT
CAATGAACTTATAAAGGACATTGATTGGAACGGTAATGAAGGGAAAGGCAAGCCTGAACCTTTAAAGCATGAATTACAAG
GATTGTGGAGCAGGCGTATAACCGCAGAACATCGTTTGATTTATAAAATTGACGATAAAAATATTTATATTCTTCAATGT
CGGGGACACTACGACGATTAA

Antitoxin

Nucleotide

• Length: 60 bp

>AT141797 NZ_CP045435:c1975256-1975197 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin