Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 1877888..1878539 Replicon chromosome
Accession NZ_CP045216
Organism Pantoea dispersa strain BJQ0007

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag GAY20_RS08735 Protein ID WP_141496026.1
Coordinates 1877888..1878232 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID A0A8E1S3S0
Locus tag GAY20_RS08740 Protein ID WP_058758775.1
Coordinates 1878225..1878539 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GAY20_RS08730 1874105..1877785 + 3681 WP_152391535.1 autotransporter outer membrane beta-barrel domain-containing protein -
GAY20_RS08735 1877888..1878232 + 345 WP_141496026.1 toxin Toxin
GAY20_RS08740 1878225..1878539 + 315 WP_058758775.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
GAY20_RS08745 1878668..1879093 + 426 WP_058781446.1 DUF393 domain-containing protein -
GAY20_RS08750 1879090..1879518 - 429 WP_058781447.1 arsenate reductase (glutaredoxin) -
GAY20_RS08755 1879536..1880819 - 1284 WP_152390818.1 arsenic transporter -
GAY20_RS08760 1880888..1881241 - 354 WP_021509466.1 metalloregulator ArsR/SmtB family transcription factor -
GAY20_RS08765 1881590..1882885 + 1296 WP_152390819.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(43-88)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13451.21 Da        Isoelectric Point: 9.6738

>T141511 WP_141496026.1 NZ_CP045216:1877888-1878232 [Pantoea dispersa]
MQATFIELSSFQKYRADYLSDDQFRLFQNMLLADPEKGDVIPDTGGLRKVRFRDERRNKGSRGGIRVIYYWTNEKGQFIL
FSIYDKDQRDDLTKQQRDALAEALNVIKKGLRHD

Download         Length: 345 bp

>T141511 NZ_CP059995:3772091-3772669 [Pseudomonas aeruginosa]
ATGTCCCTCGAACTGCTGAGCAACCGCCTCGAATTCCTCCGCGAAGCCGAACGCCTGAAAGACGTCCTGCGCTCCGCGCA
CACCTCCTCCGGTCGCCCGGAAAGCACCGCCGAACACAGTTGGCGGCTGTGCCTGATGGCTCTGGCCTTCGAGGACCAAC
TGGGCGGCCTGGACCTCGGCAAGGTCTTGCGCATGTGCGTGGTCCACGACCTCGGCGAAGCGATCCACGGCGACATCCCC
GCCGTCGAGCAGGCCGCGCACCCGGACAAGGGCGAACAGGAACGCGCCGACCTGTTGCAGCTGACCCGTCATCTGGACGC
GCCGCTGCGCGACCGCCTGCTCGCCCTGTGGGACGAATACGAGCGCGGCGAGTCCGCCGAAGCCCTGGCAGTGAAGGCCC
TGGACAAGCTGGAAACCCTGCTCCAGCACACCCAGGGCGACAATCCGGCGGACTTCGACTATGCCTTCAACCTCGACTAC
GGTCGTCGCTATACCGACCGCGCACCGCTGTTCAAGGCCCTGCGCGAGCTACTCGACGCCAGGACCCGACAGCGCCTCGC
AGCTCGGCGCGACGCCTAG

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11984.71 Da        Isoelectric Point: 8.5238

>AT141511 WP_058758775.1 NZ_CP045216:1878225-1878539 [Pantoea dispersa]
MTERDIFSELMAGMQELKDHQDGKITLKTYKVSKRAPVTIAPQELRDVREKLNLSQAVFAHYLHTGETTYQNWEQGRAKP
NAQAVLLIRMVQQNPETLQTLAQF

Download         Length: 315 bp

>AT141511 NZ_CP059995:3771449-3772003 [Pseudomonas aeruginosa]
ATGACCGAGCCTCTTCCCTCTTCGTCCCTGGGCCCCGCCCTGCGCCGCTGGCGCCTGCTGCACCGGGTCAAGCAAACGCA
TGCCGCCGAATTGCTCGGCGTGGCGCAATCGACCATCTCACGCTGGGAGTCCGGTACCCAGGCGCTGCTGGGGGAGGAAC
GGGCACGCCTGGAGCGTCTGCTCGGCGCCCGCCTGGAAGCCGCCGCCGACCAGGCACTGGCCCGCCTGGTCGAGGCCAAC
CCGCAACCCGTGCACCTGATCTGCGACCTCACCCATCGCTTGCTGGCCTGTTCGCCGACACGCGCCGCGCAATTCGGCGT
GCCCCTCGGCGAACTGCTCGACCGTTCGCTGTGGCCCTATTGCAGCGAGGAAATCCTCCGCCAGGAAGCCACCCTCGAGG
AACTCGGCTGGCGCGAACTGCTGGCACCGCCGGCGCTGGAGTTCGCCAGCGGAGCGAACACCTCGGCCATCGTGCCGATC
CGGCGCAGCCGTTGCCGCTGGACCCGCATGACCCTCTCGGACGGACGCGCGGTACGCCTGGTGGAAACCCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References