Detailed information of TA system TA141363

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 2628330..2628478
• Replicon: chromosome
• Accession: NZ_CP045187
• Organism: Staphylococcus haemolyticus strain VB19458

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: D5R78_RS12870
• Protein ID: WP_011276848.1
• Coordinates: 2628330..2628425 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2628443..2628478 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
D5R78_RS13390	2624084..2624341	+	258	Protein_2497	replication initiation protein	-
D5R78_RS12850	2624949..2626113	-	1165	Protein_2498	IS256 family transposase	-
D5R78_RS12855	2626269..2626799	+	531	WP_011276845.1	N-acetyltransferase	-
D5R78_RS12860	2627039..2627422	+	384	WP_011276846.1	effector binding domain-containing protein	-
D5R78_RS12865	2627561..2627865	+	305	Protein_2501	hypothetical protein	-
D5R78_RS13395	2627989..2628135	+	147	WP_000668388.1	hypothetical protein	-
D5R78_RS12870	2628330..2628425	+	96	WP_011276848.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	2628443..2628478	+	36	-	-	Antitoxin
D5R78_RS12875	2628619..2629278	+	660	WP_011276849.1	nucleotidyltransferase	-
D5R78_RS12880	2629524..2630126	+	603	WP_011276850.1	hypothetical protein	-
D5R78_RS12885	2630486..2631331	-	846	WP_000733283.1	BlaZ family penicillin-hydrolyzing class A beta-lactamase PC1	-
D5R78_RS12890	2631438..2633195	+	1758	WP_011276042.1	beta-lactam sensor/signal transducer BlaR1	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	IScluster/Tn	blaZ	-	2621581..2631331	9750

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3623.38 Da
• Isoelectric Point: 9.5124

>T141363 WP_011276848.1 NZ_CP045187:2628330-2628425 [Staphylococcus haemolyticus]
MLEILVHITTTVISGCIIALFTHWLRNRKDK

Nucleotide

• Length: 96 bp

>T141363 NZ_CP059955:c1262332-1261013 [Pectobacterium brasiliense]
ATGGCTGCTCTCGATGTTTACATGAACGGCTATCGGGTGGGGATTCTGACCAAAACGGGCAGTGGGGCACATCATTTTTC
CTATGATACGAACTGGCTCGGATTGCTGGGGAGTCGCCCCATTTCGCTTTCTATGCCGCTACGTCATCAGCCCTATCAAG
GCGATGAAGTTTATAACTTCTTCGACAATTTGTTGCCGGATAACCCGGATATCAGAAGACGGATTGTCGCCAGGCATCAT
ACGGATTCCACCCAACCGTTTGATCTGCTCGCTAAAGTGGGGCAAGACAGTGTCGGGGCGTTGCAATTAGTGCCGCAGGG
TACACCTGTGCACGATATAAAAAAGATCGAATATAAAACCTTATCCGAGCAGCAGCTTGAAAACATACTGACCGGATATT
TGTCCGATGCCCCGCTGGGTATGATTGATACTGAAGACGATTTTCGTATTTCTATCGCAGGTGCACAGGAAAAGACGGCA
TTGCTTTATCTGGATGATCGCTGGTGCCTGCCTCTCAATGTCACACCAACTACCCACATCATCAAGCTACCGATTGGTAA
AATCGAGAGTCACTCTTACTCAATTGATATGTCTGACAGCGTTGAAAATGAGTATCTGTGTTTGCTCATTGCCAAGGCAT
TTGGGCTGCCAGTGCCGCACTGTTTTATGATCAACGCTGGCAAGATAAAGGCGTTAGCGGTGGAGCGTTTTGATCGTAAA
TACGCCTCGGATGTCAGTTGGATTATGCGGCTACCACAAGAGGATTTTTGTCAGGTATTAAACGTTCCTTCCGCACTGAA
ATATGAAAATCATGGTGGACCGGGTATTTCCGCCATTATGTCGTTTCTATTGGGTTCGGTTTATCCAGAAAGAGATCGTT
ATCGCTTTATGCAGACTCAGGTACTGTTTTGGCTATTGGCTGCAACGGATGGTCATGCGAAAAACTTTTCCCTGTTTATT
GAATCTGAGGGACGATATCGACTCACGCCTTTCTATGACATTCTCTCTATGTATCCGGCGATGGGCGGACGGGGAATTGA
CCGCAGAGAGGCCAAACTGGCGATGGGATTAACTGGCTCAAGAGGCAAGAAATATGCGATTGAGCAGATCTTTCCCCGAC
ATTTTTTCCAGACGGCCAAGGTCGTTGGGTTCGCCAGAGAATCGATGGAAAACATTCTGGCGGAGTTTGCCCAGACCGTT
GATACCGTCATGACGACTGTTGGAAGTCAACTGCCTGTGGATTTTCCTACTCATATCAGTGAGGCAATTCTGGCCGGATT
GCAGGCCAGATCGAGACGGCTCATGAGCGGATGGGAGTAA

Antitoxin

Nucleotide

• Length: 36 bp

>AT141363 NZ_CP045187:2628443-2628478 [Staphylococcus haemolyticus]
TACAACAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin