Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) fst-RNAII/-
Location 2789698..2789893 Replicon chromosome
Accession NZ_CP045045
Organism Enterococcus faecalis strain JY32

Toxin (Protein)


Gene name fst Uniprot ID -
Locus tag F9293_RS13295 Protein ID WP_015543884.1
Coordinates 2789698..2789793 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 2789828..2789893 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F9293_RS13275 2784875..2785990 + 1116 WP_002377910.1 FAD-binding oxidoreductase -
F9293_RS13280 2786059..2787213 - 1155 WP_002355280.1 mannitol-1-phosphate 5-dehydrogenase -
F9293_RS13285 2787228..2787665 - 438 WP_002355279.1 PTS sugar transporter subunit IIA -
F9293_RS13290 2787680..2789452 - 1773 WP_002391520.1 PTS mannitol transporter subunit IICBA -
F9293_RS13295 2789698..2789793 + 96 WP_015543884.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2789828..2789893 - 66 - - Antitoxin
F9293_RS13300 2790051..2790485 - 435 WP_002355276.1 PTS sugar transporter subunit IIA -
F9293_RS13305 2790496..2792529 - 2034 WP_002355275.1 transcription antiterminator -
F9293_RS13310 2792520..2794262 - 1743 WP_002401739.1 PTS transporter subunit EIIC -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-35)


Sequences


Toxin        


Download         Length: 32 a.a.        Molecular weight: 3659.47 Da        Isoelectric Point: 4.6275

>T141139 WP_015543884.1 NZ_CP045045:2789698-2789793 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Download         Length: 96 bp

>T141139 NZ_CP059835:c5012973-5012866 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 66 bp

>AT141139 NZ_CP045045:c2789893-2789828 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATCAGTAGTAGGGTGTCTTTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References